Pediatric pharmacodynamics of midazolam oral syrup
J Marshall, A Rodarte, J Blumer… - The Journal of …, 2000 - Wiley Online Library
In this study, the authors evaluate the pharmacodynamics, safety, and acceptability of a new
cherry‐flavored oral syrup formulation of midazolam. This randomized, double‐blind …
cherry‐flavored oral syrup formulation of midazolam. This randomized, double‐blind …
A comparison of three doses of a commercially prepared oral midazolam syrup in children
CJ Coté, IT Cohen, S Suresh, M Rabb… - Anesthesia & …, 2002 - journals.lww.com
Midazolam is widely used as a preanesthetic medication for children. Prior studies have
used extemporaneous formulations to disguise the bitter taste of IV midazolam and to …
used extemporaneous formulations to disguise the bitter taste of IV midazolam and to …
Midazolam premedication in children: a comparison of two oral dosage formulations on sedation score and plasma midazolam levels
KK Brosius, CF Bannister - Anesthesia & Analgesia, 2003 - journals.lww.com
We compared two available oral formulations of midazolam with respect to sedation score
and plasma midazolam levels in pediatric surgical patients 2–10 yr old. The commercially …
and plasma midazolam levels in pediatric surgical patients 2–10 yr old. The commercially …
A novel, palatable paediatric oral formulation of midazolam: pharmacokinetics, tolerability, efficacy and safety
Midazolam is one of many bitter drugs where provision of a suitable oral paediatric
formulation, particularly in the pre‐anaesthetic setting, remains a challenge. To overcome …
formulation, particularly in the pre‐anaesthetic setting, remains a challenge. To overcome …
The single‐dose pharmacokinetics of midazolam and its primary metabolite in pediatric patients after oral and intravenous administration
The first‐dose pharmacokinetics of midazolam and its primary α‐hydroxy metabolite were
studied after single‐dose administration. Eligible study patients were enrolled into one of …
studied after single‐dose administration. Eligible study patients were enrolled into one of …
Clinical pharmacology of midazolam in neonates and children: effect of disease—a review
GM Pacifici - International journal of pediatrics, 2014 - Wiley Online Library
Midazolam is a benzodiazepine with rapid onset of action and short duration of effect. In
healthy neonates the half‐life (t1/2) and the clearance (Cl) are 3.3‐fold longer and 3.7‐fold …
healthy neonates the half‐life (t1/2) and the clearance (Cl) are 3.3‐fold longer and 3.7‐fold …
Premedication of children with oral midazolam
CO McMillan, IA Spahr-Schopfer, N Sikich… - Canadian Journal of …, 1992 - Springer
In a randomized, double-blind, placebo-controlled study, the safety, efficacy and feasibility of
oral midazolam premedication in children were evaluated in an ambulatory surgery unit …
oral midazolam premedication in children were evaluated in an ambulatory surgery unit …
[HTML][HTML] Premedication with midazolam nasal spray: an alternative to oral midazolam in children
RK Verma, A Paswan, A De, S Gupta - Anesthesiology and pain …, 2012 - ncbi.nlm.nih.gov
Background: Midazolam is a water soluble benzodiazepine which is frequently administered
by intravenous and oral routes in our institution. Its nasal spray has become recently …
by intravenous and oral routes in our institution. Its nasal spray has become recently …
Oral midazolam in children: effect of time and adjunctive therapy
BC Weldon, MF Watcha, PF White - Anesthesia & Analgesia, 1992 - journals.lww.com
The purpose of this study was to determine the influence of timing and concomitant
administration of atropine and/or meperidine on the perioperative effects of oral midazolam …
administration of atropine and/or meperidine on the perioperative effects of oral midazolam …
Premedication with oral midazolam in children—an assessment of psychomotor function, anxiolysis, sedation and pharmacokinetics
RDM Jones, AR Visram, JP Kornberg… - … and intensive care, 1994 - journals.sagepub.com
We studied 30 children, aged 4 to 12 years, undergoing elective circumcision, premedicated
with midazolam 0.5 mg. kg− 1 and atropine 0.02 mg. kg− 1 by mouth. A modified postbox …
with midazolam 0.5 mg. kg− 1 and atropine 0.02 mg. kg− 1 by mouth. A modified postbox …
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