Genetic predisposition accounts for≥ 10% of all cancer of the prostate (CaP) and is
therefore considered a major risk factor, together with age and ethnic origin. Several …

Background: Diagnosis with prostate cancer has been reported to increase the risk of
subsequent tumours. However, specific data on individuals with a parental history are not …

One of the triumphs of molecular genetics during the past two decades has been the
elucidation of the molecular mechanisms responsible for the inherited predisposition for a …

BACKGROUND: The thorough assessment of familial prostate cancer (PCa) risk is as
important as ever to provide a basis for clinical counselling and screening …

Purpose: There are few data regarding the epidemiology of hereditary or familial prostate
cancer (PCa) in East Asians, especially in Korean men. Therefore, we evaluated the …

Multiple factors contribute to the high incidence and prevalence of prostate cancer including
race, ethnicity, diet, environment, widespread awareness through prostate-specific antigen …

Prostate cancer is currently the most commonly diagnosed malignancy in American men.
Approximately 38,000 men die from this disease annually in this country (Boring et al. 1994) …

Prostate cancer has been known to run in families for about 40 years and epidemiological
studies have demonstrated an increased risk to close relatives of cases. This risk rises …

Abstract The Swedish Family-Cancer Database has been used for some 10 years in the
study of familial risks at all common sites. In the present paper we describe some of the main …

Prostate cancer (PCa) has a large familial component, but understanding of its genetic basis
is fragmentary. Breast cancers may be associated with PCa, but whether this is true for other …