In this study, a series of aspartate based dendrimers with different cores were synthesized in
a convergent approach and well characterized by NMR and MS techniques. The aqueous …

Poor solubility and hydrophobicity of drugs/bioactives limit their possible applications in drug
delivery and formulation development. Apart from conventional methods of solubility …

Classic dendrimers are not used in many specific applications such as simultaneous loading
of different drugs due to the existence of identical end groups. The possibility of designing …

The interactions between dendrimers and different types of drugs are nowadays one of the
most actively investigated areas of the pharmaceutical sciences. The interactions between …

Adequate aqueous solubility has been one of the desired properties while selecting drug
molecules and other bio-actives for product development. Often solubility of a drug …

In the present study we investigated the effect of ethylenediamine (EDA) core
polyamidoamine (PAMAM) dendrimers on the aqueous solubility of nicotinic acid. The …

A drug is effective in their molecular form; thus solubility in the biological fluid is important.
Pharmaceutical researchers are continuously working on the improvement of solubility of …

Dendrimers are 3D, hyperbranched, tree-like polymers having immense potential in drug
delivery, targeting, diagnosis and as carriers for DNA/gene delivery. Dendrimers have …

Methods: s-triazine based dendrimer was synthesized up to generation 3 by divergent
method. Synthesized dendrimer generations were characterized by IR, 1H-NMR, 13C-NMR …

Dendrimers today are known for their three dimensional, monodispersed, highly branched,
macromolecular nano-scopic architecture with number of reactive end groups. Dendrimers …