Rationale: Chronic rejection, manifested pathologically as airway fibrosis, is the major
problem limiting long-term survival in lung transplant recipients. Airway hypoxia and …

Rationale: The chronic rejection of lung allografts is attributable to progressive small airway
obstruction. Objectives: To determine precisely the site and nature of this type of airway …

Background: In asthma there has been increasing interest in the contribution of airway
microvasculature to airway wall thickness and lumenal narrowing. Post-lung transplant, the …

Rationale: Central airway stenosis (CAS) after lung transplantation has been attributed in
part to chronic airway ischemia; however, little is known about the time course or …

Bronchiolitis obliterans, defined histologically or clinically, is the most significant long-term
cause of morbidity and mortality after lung transplantation. It shares many pathogenetic …

A dual circulation, supplied by bronchial and pulmonary artery-derived vessels, normally
perfuses the airways from the trachea to the terminal bronchioles. This vascular system has …

The development of spirometric airflow obstruction may be a diagnostic dilemma in
recipients of single lung allografts. The contribution of bronchial anastomotic stenosis to the …

With the interruption of the bronchial arteries after lung transplantation, nutritive support is
dependent on collateral flow by the pulmonary arteries with desaturated venous blood …

Background: Following successful lung transplantation, most of the lung perfusion, as well
as ventilation, is shifted towards the transplanted lung. We investigated the changes in …

Background The early postoperative course of single-lung transplant recipients depends on
the recipient's underlying lung pathophysiology and the degree of ischemic-reperfusion …