Direct oral anticoagulants in patients with nonvalvular atrial fibrillation and low body weight

SR Lee, EK Choi, CS Park, KD Han, JH Jung… - Journal of the American …, 2019 - jacc.org
Background: It is unclear whether the overall effectiveness and safety of direct oral
anticoagulants (DOACs) are consistent in patients with nonvalvular atrial fibrillation (AF) and …

Is There an Obesity Paradox for Outcomes in Atrial Fibrillation? A Systematic Review and Meta-Analysis of Non–Vitamin K Antagonist Oral Anticoagulant Trials

M Proietti, E Guiducci, P Cheli, GYH Lip - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Obesity is a risk factor for all-cause and cardiovascular death
but, despite this, an inverse relationship between overweight or obesity and a better …

A single center retrospective cohort study evaluating use of direct oral anticoagulants (DOACs) in morbidly obese veteran population

T Patil, M Lebrecht - Thrombosis research, 2020 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are preferred over warfarin for the
treatment of venous thromboembolism (VTE) as well as atrial fibrillation (AF). The efficacy …

Thromboembolic and bleeding risk in obese patients with atrial fibrillation according to different anticoagulation strategies

G Patti, L Pecen, MC Manu, K Huber, M Rohla… - International Journal of …, 2020 - Elsevier
Background Data on the relationship between body mass index (BMI), thromboembolic
events (TEE) and bleeding in patients with atrial fibrillation (AF) are controversial, and further …

Association between body mass index and clinical outcomes in patients with non-valvular atrial fibrillation receiving direct oral anticoagulants: a new piece of …

S Wu, N Huang, X Chen, S Jiang, W Zhang… - … Drugs and Therapy, 2023 - Springer
Purpose We conducted a multicenter real-world study in China to assess the association
between body mass index (BMI) and clinical outcomes in patients with atrial fibrillation (AF) …

Efficacy and safety of direct oral anticoagulants for atrial fibrillation across body mass index categories

RM Kaplan, Y Tanaka, RS Passman… - Journal of the …, 2020 - Am Heart Assoc
Background Direct‐acting oral anticoagulants are now the preferred method of
anticoagulation in patients with atrial fibrillation. Limited data on efficacy and safety of these …

Non-vitamin K antagonist oral anticoagulants (NOACs) versus warfarin in patients with atrial fibrillation and (morbid) obesity or low body weight: a systematic review …

M Grymonprez, TL De Backer, S Steurbaut… - … Drugs and Therapy, 2021 - Springer
Purpose Oral anticoagulants are crucial for preventing systemic thromboembolism in atrial
fibrillation (AF), with guidelines preferring non-vitamin K antagonist oral anticoagulants …

Direct oral anticoagulants in patients with nonvalvular atrial fibrillation and extreme body weight

F Bodega, A Russi, F Melillo, F Blunda… - European Journal of …, 2022 - Wiley Online Library
Background Limited clinical data exist describing the use of direct oral anticoagulants
(DOACs) in patient with extreme body weight. Thus, the International Society of Thrombosis …

Evaluation of the efficacy of direct oral anticoagulants (DOACs) in comparison to warfarin in morbidly obese patients

C Kalani, E Awudi, T Alexander, G Udeani… - Hospital …, 2019 - Taylor & Francis
Purpose: There is limited clinical data evaluating anticoagulation with the direct oral
anticoagulants (DOACs) in morbidly obese patients. We sought to examine the efficacy in …

Increased risk of major bleeding in underweight patients with atrial fibrillation who were prescribed non-vitamin K antagonist oral anticoagulants

CS Park, EK Choi, HM Kim, SR Lee, MJ Cha, S Oh - Heart Rhythm, 2017 - Elsevier
Background There is a paucity of evidence regarding the effects of non-vitamin K antagonist
oral anticoagulants (NOACs) in underweight patients with atrial fibrillation (AF). Objective …