Performance evaluation of PAMAM dendrimer based simvastatin formulations
The purpose of this investigation was to evaluate the performance of poly
(amidoamine)(PAMAM) dendrimers, with three different surface groups, to be used as drug …
(amidoamine)(PAMAM) dendrimers, with three different surface groups, to be used as drug …
Pharmacokinetic and pharmacodynamic studies of poly (amidoamine) dendrimer based simvastatin oral formulations for the treatment of hypercholesterolemia
H Kulhari, DP Kulhari, SK Prajapati… - Molecular …, 2013 - ACS Publications
The aim of this investigation was to evaluate the in vivo potential of poly (amidoamine)
dendrimers (PAMAM) based simvastatin (SMV) formulations as nanoscale drug delivery …
dendrimers (PAMAM) based simvastatin (SMV) formulations as nanoscale drug delivery …
Poly (amidoamine) dendrimer-mediated hybrid formulation for combination therapy of ramipril and hydrochlorothiazide
We present a dendrimer-based hybrid formulation strategy to explore the potential of poly
(amidoamine) PAMAM dendrimers to be used as drug carriers for combination therapy of an …
(amidoamine) PAMAM dendrimers to be used as drug carriers for combination therapy of an …
Dendrimers as versatile platform in drug delivery applications
S Svenson - European Journal of Pharmaceutics and …, 2009 - Elsevier
About forty percent of newly developed drugs are rejected by the pharmaceutical industry
and will never benefit a patient because of poor bioavailability due to low water solubility …
and will never benefit a patient because of poor bioavailability due to low water solubility …
PAMAM dendrimers in drug delivery: Loading efficacy and polymer morphology
P Chanphai, L Bekale… - Canadian Journal of …, 2017 - cdnsciencepub.com
The binding efficacy of anticancer drugs doxorubicin and tamoxifen with polyamidoamine
(PAMAM-G4) dendrimers was studied in aqueous solution at physiological pH. The results …
(PAMAM-G4) dendrimers was studied in aqueous solution at physiological pH. The results …
[PDF][PDF] Dendrimers as potential platform in nanotechnology-based drug delivery systems
NP Silva, FP Menacho, M Chorilli - IOSR journal of pharmacy, 2012 - researchgate.net
The dendrimers of poly (amidoamine)(PAMAM) are nanoparticles which have proven
succeed in transporting drugs due to high solubility, low toxicity and ability to control drugs …
succeed in transporting drugs due to high solubility, low toxicity and ability to control drugs …
[PDF][PDF] Dendrimers and their applications as novel drug delivery carriers
S Tripathy, MK Das - Journal of Applied Pharmaceutical Science, 2013 - japsonline.com
Dendrimers are novel synthetic polymeric systems having improved physical and chemical
properties due to their unique three dimensional architecture. Dendrimers have a well …
properties due to their unique three dimensional architecture. Dendrimers have a well …
Dendrimers as an effective nanocarrier in cardiovascular disease
In the last two decades, dendrimers have proven their capabilities in drug delivery, physical
stabilization of the drug, solubility enhancement of the poorly soluble drugs and gene …
stabilization of the drug, solubility enhancement of the poorly soluble drugs and gene …
Application of dendrimer–drug complexation in the enhancement of drug solubility and bioavailability
NK Jain, U Gupta - Expert opinion on drug metabolism & toxicology, 2008 - Taylor & Francis
Dendrimers are 3D, hyperbranched, tree-like polymers having immense potential in drug
delivery, targeting, diagnosis and as carriers for DNA/gene delivery. Dendrimers have …
delivery, targeting, diagnosis and as carriers for DNA/gene delivery. Dendrimers have …
Dendrimers as drug delivery vehicles: non‐covalent interactions of bioactive compounds with dendrimers
HL Crampton, EE Simanek - Polymer international, 2007 - Wiley Online Library
This mini review highlights issues associated with the use of dendrimers as drug delivery
vehicles. The review introduces dendrimers and summarizes findings on their use in vivo …
vehicles. The review introduces dendrimers and summarizes findings on their use in vivo …