The interplay between DNA methylation and sequence divergence in recent human evolution
I Hernando-Herraez, H Heyn… - Nucleic acids …, 2015 - academic.oup.com
Despite the increasing knowledge about DNA methylation, the understanding of human
epigenome evolution is in its infancy. Using whole genome bisulfite sequencing we …
epigenome evolution is in its infancy. Using whole genome bisulfite sequencing we …
A comparative analysis of DNA methylation across human embryonic stem cell lines
Background We performed a comparative analysis of the genome-wide DNA methylation
profiles from three human embryonic stem cell (HESC) lines. It had previously been shown …
profiles from three human embryonic stem cell (HESC) lines. It had previously been shown …
Reversible regulation of promoter and enhancer histone landscape by DNA methylation in mouse embryonic stem cells
DNA methylation is one of a number of modes of epigenetic gene regulation. Here, we
profile the DNA methylome, transcriptome, and global occupancy of histone modifications …
profile the DNA methylome, transcriptome, and global occupancy of histone modifications …
Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development
M Sen, D Mooijman, A Chialastri, JC Boisset… - Nature …, 2021 - nature.com
DNA methylation (5mC) is central to cellular identity. The global erasure of 5mC from the
parental genomes during preimplantation mammalian development is critical to reset the …
parental genomes during preimplantation mammalian development is critical to reset the …
DNA methylation-based variation between human populations
F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …
development. Epigenome-wide studies have reported variation in methylation patterns …
Variability of genome-wide DNA methylation and mRNA expression profiles in reproductive and endocrine disease related tissues
Genome-wide association studies in the fields of reproductive medicine and endocrinology
are yielding robust genetic variants associated with disease. Integrated genomic …
are yielding robust genetic variants associated with disease. Integrated genomic …
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
Birthweight is associated with health outcomes across the life course, DNA methylation may
be an underlying mechanism. In this meta-analysis of epigenome-wide association studies …
be an underlying mechanism. In this meta-analysis of epigenome-wide association studies …
Dynamic DNA methylation across diverse human cell lines and tissues
As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types …
a complex relationship with gene expression, plays an important role in defining cell types …
Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos
DNA methylation undergoes dynamic changes during development and cell differentiation.
Recent genome-wide studies discovered that tissue-specific differentially methylated …
Recent genome-wide studies discovered that tissue-specific differentially methylated …