Lineage-specific chimaerism quantification after T-cell depleted peripheral blood stem cell transplantation

I Buño, B Anta, E Moreno-López… - Leukemia & …, 2003 - Taylor & Francis
Patients that receive a T-cell depleted (TCD) hematopoietic stem cell transplantation (SCT)
show higher risk of graft failure/rejection and of disease relapse than those that receive …

Serial quantification of lymphoid and myeloid mixed chimerism using multiplex PCR amplification of short tandem repeat-markers predicts graft rejection and relapse …

F Fernandez-Aviles, A Urbano-Ispizua, M Aymerich… - Leukemia, 2003 - nature.com
We used multiplex amplification of nine microsatellite sequences (PCR-STR) to analyse
chimerism in pure populations of T cells and neutrophils from peripheral blood from 40 …

Significance of chimerism in hematopoietic stem cell transplantation: new variations on an old theme

F Khan, A Agarwal, S Agrawal - Bone marrow transplantation, 2004 - nature.com
The main goal of post-transplantation monitoring in hematopoietic stem cell transplantation
(HSCT) is to predict negative events, such as disease relapse, graft rejection and graft …

Relevance of Chimerism analysis after allogeneic stem cell transplantation

I Clemente, A Goncalo, C Faria, M Dias… - Transplantation …, 2017 - Elsevier
Hematopoietic stem cell transplantation is a potentially curative therapy for a range of
malignant and non-malignant hematological diseases. Analysis of chimerism following …

Sequential molecular monitoring of chimerism in chronic myeloid leukemia patients receiving donor lymphocyte transfusion for relapse after bone marrow …

MC Rapanotti, W Arcese, S Buffolino, AP Iori… - Bone marrow …, 1997 - nature.com
Recent observations of chimerism in patients relapsed following an allotransplant suggest
the persistence of immunotolerance, thus offering a biologic rationale for the use of donor …

[HTML][HTML] Achievement of early complete donor chimerism in CD25+-activated leukocytes is a strong predictor of the development of graft-versus-host-disease after …

C Martínez-Laperche, V Noriega, M Kwon… - Experimental …, 2015 - Elsevier
Chimerism dynamics in bone marrow, peripheral blood (PB), and T lymphocytes (TL) has
been associated with the development of various complications after allogeneic stem-cell …

Assessment of lineage-specific chimerism after allogeneic stem cell transplantation

P Zielińska, M Markiewicz… - Acta Haematologica …, 2014 - journals.viamedica.pl
Materials and methods The study group consisted of 12 acute leukemia patients who
underwent allo-SCT in the Department of Hematology and Bone Marrow Transplantation in …

[HTML][HTML] Characterization of mixed chimerism in patients with chronic myeloid leukemia transplanted with T-cell-depleted bone marrow: involvement of different …

E Roux, K Abeti, D Speiser, C Helg, B Chapuis… - Blood, 1993 - Elsevier
We have characterized mixed chimerism (MC) in five patients with chronic myeloid leukemia
(CML) who received transplants with T-cell—depleted bone marrow (BM) and who relapsed …

[HTML][HTML] Prognostic utility of routine chimerism testing at 2 to 6 months after allogeneic hematopoietic cell transplantation

GI Mossallam, AM Kamel, B Storer, PJ Martin - Biology of Blood and …, 2009 - Elsevier
The utility of routine chimerism analysis as a prognostic indicator of subsequent outcomes
after allogeneic hematopoietic cell transplantation (HCT) with myeloablative conditioning …

Monitoring of lineage-specific chimaerism allows early prediction of response following donor lymphocyte infusions for relapsed chronic myeloid leukaemia

N Gardiner, M Lawler, JM O'Riordan… - Bone marrow …, 1998 - nature.com
Donor lymphocyte infusions (DLI) have been shown to enhance the graft-versus-leukaemia
(GVL) effect and induce haematological and molecular remission in patients with relapsed …