Heart-type fatty acid-binding protein reciprocally regulates glucose and fatty acid utilization during exercise

J Shearer, PT Fueger, JN Rottman… - American Journal …, 2005 - journals.physiology.org
The role of heart-type cytosolic fatty acid-binding protein (H-FABP) in mediating whole body
and muscle-specific long-chain fatty acid (LCFA) and glucose utilization was examined …

Requirement for the heart‐type fatty acid binding protein in cardiac fatty acid utilization

B Binas, H Danneberg, JIM McWhir… - The FASEB …, 1999 - Wiley Online Library
Nonenzymatic cytosolic fatty acid binding proteins (FABPs) are abundantly expressed in
many animal tissues with high rates of fatty acid metabolism. No physiological role has been …

Nonacute effects of H-FABP deficiency on skeletal muscle glucose uptake in vitro

E Erol, GW Cline, JK Kim… - American Journal of …, 2004 - journals.physiology.org
Heart-type fatty acid-binding protein (H-FABP) is required for high rates of skeletal muscle
long-chain fatty acid (LCFA) oxidation and esterification. Here we assessed whether H …

Impaired long-chain fatty acid utilization by cardiac myocytes isolated from mice lacking the heart-type fatty acid binding protein gene

FG Schaap, B Binas, H Danneberg… - Circulation …, 1999 - Am Heart Assoc
Heart-type fatty acid binding protein (H-FABP), abundantly expressed in cardiac myocytes,
has been postulated to facilitate the cardiac uptake of long-chain fatty acids (LCFAs) and to …

[HTML][HTML] Metabolic implications of reduced heart-type fatty acid binding protein in insulin resistant cardiac muscle

J Shearer, PT Fueger, ZZ Wang, DP Bracy… - … et Biophysica Acta (BBA …, 2008 - Elsevier
Insulin resistance is characterized by elevated rates of cardiac fatty acid utilization resulting
in reduced efficiency and cardiomyopathy. One potential therapeutic approach is to limit the …

Transcriptional regulation of muscle fatty acid-binding protein

JO Carey, PD Neufer, RP Farrar… - Biochemical …, 1994 - portlandpress.com
Heart fatty acid-binding protein (H-FABP) is present in a wide variety of tissues but is found
in the highest concentration in cardiac and red skeletal muscle. It has been proposed that …

Long-chain fatty acid uptake by skeletal muscle is impaired in homozygous, but not heterozygous, heart-type-FABP null mice

J Luiken, DPY Koonen, WA Coumans, M Pelsers… - Lipids, 2003 - Springer
Previous studies with cardiac myocytes from homozygous heart-type fatty acid (FA)-binding
protein (H-FABP)−/− mice have indicated that this intracellular: receptor protein for long …

A null mutation in H-FABP only partially inhibits skeletal muscle fatty acid metabolism

B Binas, XX Han, E Erol, JJFP Luiken… - American Journal …, 2003 - journals.physiology.org
The low-molecular-mass, cytosolic heart-type fatty acid-binding protein (H-FABP) is thought
to be required for shuttling FA through the cytosol. Therefore, we examined the effects of an …

Partial gene deletion of heart-type fatty acid–binding protein limits the severity of dietary-induced insulin resistance

J Shearer, PT Fueger, DP Bracy, DH Wasserman… - Diabetes, 2005 - Am Diabetes Assoc
The aim of this study was to determine the contribution of heart-type fatty acid–binding
protein (H-FABP) to glucose and long-chain fatty acid (LCFA) utilization in dietary-induced …

Cytoplasmic fatty acid‐binding protein facilitates fatty acid utilization by skeletal muscle

JFC Glatz, FG Schaap, B Binas, A Bonen… - Acta Physiologica …, 2003 - Wiley Online Library
The intracellular transport of long‐chain fatty acids in muscle cells is facilitated to a great
extent by heart‐type cytoplasmic fatty acid‐binding protein (H‐FABP). By virtue of the …