We compared two available oral formulations of midazolam with respect to sedation score
and plasma midazolam levels in pediatric surgical patients 2–10 yr old. The commercially …

Midazolam is a parenteral benzodiazepine with sedative, amnesic, anxiolytic, muscle
relaxant and anticonvulsant properties. The drug exerts its clinical effect by binding to a …

Midazolam is frequently used to produce sedation in critically ill pediatric patients. We
studied the pharmacokinetics of midazolam in 22 patients (age 8 days to 16 years). The …

Background Because information on the optimal dose of midazolam for sedation of
nonventilated infants after major surgery is scant, a population pharmacokinetic and …

Background: We undertook a study to determine the effects of four routes of administation on
the efficacy of midazolam for premedication. Methods: In a randomized double‐blind study …

Midazolam is one of many bitter drugs where provision of a suitable oral paediatric
formulation, particularly in the pre‐anaesthetic setting, remains a challenge. To overcome …

In this study, the authors evaluate the pharmacodynamics, safety, and acceptability of a new
cherry‐flavored oral syrup formulation of midazolam. This randomized, double‐blind …

Background Preanesthetic medication is important to eliminate surgical anxiety in pediatric
patients and facilitate their smooth transfer to the operating room. Midazolam is the most …

We studied 30 children, aged 4 to 12 years, undergoing elective circumcision, premedicated
with midazolam 0.5 mg. kg− 1 and atropine 0.02 mg. kg− 1 by mouth. A modified postbox …

The question of whether premedication should be routinely used in pediatric patients has
recently been the focus of debate among pediatric anesthetists. Although most of us have …