In vivo genome editing targeted towards the female reproductive system

M Sato, M Ohtsuka, S Nakamura, T Sakurai… - Archives of pharmacal …, 2018 - Springer
The discovery of sequence specific nucleases such as ZFNs, TALENs, and CRISPR/Cas9
has revolutionized genome editing. The CRISPR/Cas9 system has particularly emerged as …

[HTML][HTML] Use of gene-editing technology to introduce targeted modifications in pigs

J Ryu, RS Prather, K Lee - Journal of animal science and biotechnology, 2018 - Springer
Pigs are an important resource in agriculture and serve as a model for human diseases. Due
to their physiological and anatomical similarities with humans, pigs can recapitulate …

[HTML][HTML] Improvements in gene editing technology boost its applications in livestock

IV Perisse, Z Fan, GN Singina, KL White… - Frontiers in …, 2021 - frontiersin.org
Accelerated development of novel CRISPR/Cas9-based genome editing techniques
provides a feasible approach to introduce a variety of precise modifications in the …

[HTML][HTML] How genome editing changed the world of large animal research

K Fischer, A Schnieke - Frontiers in Genome Editing, 2023 - frontiersin.org
The first genetically modified large animals were developed in 1985 by microinjection to
increase the growth of agricultural livestock such as pigs. Since then, it has been a difficult …

[PDF][PDF] The promises and challenges of precision gene editing in animals of agricultural importance

PB Hackett, SC Fahrenkrug, DF Carlson - 2014 - ecommons.cornell.edu
The Promises and Challenges of Precision Gene Editing in Animals of Agricultural Importance
Page 1 3 We live in changing times—it has always been that way. But, now the times are …

Genome editing: state of the art and application to animal husbandry.

NA Zinovieva, NA Volkova, VA Bagirov - 2018 - cabidigitallibrary.org
The creation and development of genome editing (GE) technologies open new opportunities
in the genetic engineering of domestic mammals and poultry. In the present review, we have …

[HTML][HTML] Application of gene editing technology in resistance breeding of livestock

S Wang, Z Qu, Q Huang, J Zhang, S Lin, Y Yang… - Life, 2022 - mdpi.com
As a new genetic engineering technology, gene editing can precisely modify the specific
gene sequence of the organism's genome. In the last 10 years, with the rapid development …

Genome centric engineering using ZFNs, TALENs and CRISPR-Cas9 systems for trait improvement and disease control in Animals

AK Wani, N Akhtar, R Singh, A Prakash… - Veterinary research …, 2023 - Springer
Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …

[HTML][HTML] Advances in genome editing for improved animal breeding: A review

SA Bhat, AA Malik, SM Ahmad, RA Shah… - Veterinary …, 2017 - ncbi.nlm.nih.gov
Since centuries, the traits for production and disease resistance are being targeted while
improving the genetic merit of domestic animals, using conventional breeding programs …

[HTML][HTML] Sheep and goat genome engineering: from random transgenesis to the CRISPR era

P Kalds, S Zhou, B Cai, J Liu, Y Wang… - Frontiers in …, 2019 - frontiersin.org
Sheep and goats are valuable livestock species that have been raised for their production of
meat, milk, fiber, and other by-products. Due to their suitable size, short gestation period …