Animal transgenesis and cloning: combined development and future perspectives

MS Yamashita, EO Melo - Somatic Cell Nuclear Transfer Technology, 2023 - Springer
The revolution in animal transgenesis began in 1981 and continues to become more
efficient, cheaper, and faster to perform. New genome editing technologies, especially …

New insights and current tools for genetically engineered (GE) sheep and goats

A Menchaca, I Anegon, CBA Whitelaw, H Baldassarre… - Theriogenology, 2016 - Elsevier
Genetically engineered sheep and goats represent useful models applied to proof of
concepts, large-scale production of novel products or processes, and improvement of animal …

Applications of genome editing on laboratory animals

C Galichet, R Lovell-Badge - Laboratory Animals, 2022 - journals.sagepub.com
For four decades, genetically altered laboratory animals have provided invaluable
information. Originally, genetic modifications were performed on only a few animal species …

Transgenesis in farm animals-A review

P Mehta, A Sharma, R Kaushik - Agricultural Reviews, 2017 - indianjournals.com
For a number of decades, attempts have been made to successfully produce transgenic
animals which have numerous applications in the biotechnology industry with the foremost …

Redesigning small ruminant genomes with CRISPR toolkit: overview and perspectives

P Kalds, Y Gao, S Zhou, B Cai, X Huang, X Wang… - Theriogenology, 2020 - Elsevier
Genetic modification is a rapidly developing field in which numerous significant
breakthroughs have been achieved. Over the last few decades, genetic modification has …

i‐GONAD: A method for generating genome‐edited animals without ex vivo handling of embryos

M Ohtsuka, M Sato - Development, Growth & Differentiation, 2019 - Wiley Online Library
The recent development of genome editing technologies has enabled the creation of
genome‐edited animals, with alterations at the desired target locus. The clustered regularly …

Generation of gene edited birds in one generation using sperm transfection assisted gene editing (STAGE)

CA Cooper, A Challagulla, KA Jenkins, TG Wise… - Transgenic …, 2017 - Springer
Generating transgenic and gene edited mammals involves in vitro manipulation of oocytes
or single cell embryos. Due to the comparative inaccessibility of avian oocytes and single …

Genome editing mediated by primordial germ cell in chicken

JY Han, HJ Lee - Genome Editing in Animals: Methods and Protocols, 2017 - Springer
Rapid development of genome editing technology has facilitated the studies on exploring
specific gene functions and establishment of model animals. In livestock, the technology has …

Genome modification technologies and their applications in avian species

HJ Lee, YM Kim, T Ono, JY Han - International Journal of Molecular …, 2017 - mdpi.com
The rapid development of genome modification technology has provided many great
benefits in diverse areas of research and industry. Genome modification technologies have …

Use of genome editing techniques to produce transgenic farm animals

AN Hay, K Farrell, CM Leeth, K Lee - Recent Advances in Animal Nutrition …, 2022 - Springer
Recombinant proteins are essential for the treatment and diagnosis of clinical human
ailments. The availability and biological activity of recombinant proteins is heavily influenced …