Synthesis of complex carbohydrates and glycoconjugates: enzyme-based and programmable one-pot strategies
KM Koeller, CH Wong - Chemical Reviews, 2000 - ACS Publications
Identifying the functional roles of carbohydrates in biological systems has been an area of
intense study in recent years. Although carbohydrates were once viewed only as inert …
intense study in recent years. Although carbohydrates were once viewed only as inert …
Glycosidases and glycosyl transferases in glycoside and oligosaccharide synthesis
DHG Crout, G Vic - Current opinion in chemical biology, 1998 - Elsevier
Remarkable advances in glycobiology in recent years have stimulated a resurgence of
interest in carbohydrate chemistry. The challenge of producing the complex glycosides and …
interest in carbohydrate chemistry. The challenge of producing the complex glycosides and …
Catalytic glycosylations in oligosaccharide synthesis
MM Nielsen, CM Pedersen - Chemical reviews, 2018 - ACS Publications
Catalytic glycosylation has been a central reaction in carbohydrate chemistry since its
introduction by Fischer 125 years ago, but it is only in the past three to four decades that …
introduction by Fischer 125 years ago, but it is only in the past three to four decades that …
New approaches to enzymatic glycoside synthesis through directed evolution
R Kittl, SG Withers - Carbohydrate research, 2010 - Elsevier
The expanding field of glycobiology requires tools for the synthesis of structurally defined
oligosaccharides and glycoconjugates, while any potential therapeutic applications of sugar …
oligosaccharides and glycoconjugates, while any potential therapeutic applications of sugar …
Toward automated synthesis of oligosaccharides and glycoproteins
P Sears, CH Wong - Science, 2001 - science.org
The discovery of previously unknown functions associated with carbohydrates and the study
of their structure-function relations are of current interest in carbohydrate chemistry and …
of their structure-function relations are of current interest in carbohydrate chemistry and …
[图书][B] Selective glycosylations: Synthetic methods and catalysts
CS Bennett - 2017 - books.google.com
A comprehensive summary of novel approaches to the stereoselective construction of
glycosidic linkages, covering modern glycosylation methods and their use and application in …
glycosidic linkages, covering modern glycosylation methods and their use and application in …
[图书][B] Modern synthetic methods in carbohydrate chemistry: From monosaccharides to complex glycoconjugates
D Crich - 2013 - books.google.com
The fields of glycochemistry and glycoscience are rich and varied and where much can be
learned from Nature. As Nature is not always able to produce carbohydrates in quantities …
learned from Nature. As Nature is not always able to produce carbohydrates in quantities …
Chemical transformations employing glycosyltransferases
U Gambert, J Thiem - Glycoscience Synthesis of Oligosaccharides and …, 2008 - Springer
Abstract Early on, Emil Fischer proposed the use and technological application of enzymes
in natural product chemistry, in particular in peptide and carbohydrate synthesis. After …
in natural product chemistry, in particular in peptide and carbohydrate synthesis. After …
Oligosaccharide synthesis and translational innovation
L Krasnova, CH Wong - Journal of the American Chemical Society, 2019 - ACS Publications
The translation of biological glycosylation in humans to the clinical applications involves
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
Toward automated enzymatic synthesis of oligosaccharides
Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …