Studies of the relationship between male infertility and CYP1A1 polymorphisms are
inconclusive. To drive a more precise estimation, we performed a meta-analysis based on …

Background Epidemiological studies have evaluated the association between 3801T> C
polymorphism of CYP1A1 gene and the risk for idiopathic male infertility, but the results are …

Summary Cytochrome P4501A1 (CYP1A1) is a key enzyme in phase I bioactivation of
polycyclic aromatic hydrocarbons (PAHs), which have potential reproductive toxicity. The …

The study was designed to investigate the associations of polymorphisms Ile462Val and
3801T> C of the cytochrome P450 1A1 (CYP1A1) gene with idiopathic male infertility (IMI) …

Background: Number of studies have been performed to investigate the relationship
between the CYP1A1 rs4646903 polymorphism and male infertility risk, but the sample size …

Genetic factors that could mediate the pathogenesis of male reproductive disorders are
largely unclear. Polymorphisms of cytochrome P4501A1 (CYP1A1), a key enzyme in the …

BACKGROUND: The CYP1A1 gene is a polymorphic gene and encodes for the CYP1A1
enzyme that catalyzes the bioactivation of polycyclic aromatic hydrocarbons (PAHs). PAHs …

BACKGROUND: It is acknowledged that Cytochrome P450 1B1 (CYP1B1) plays a crucial
role in metabolism and is involved in lots of diseases. We carried out this study to evaluate …

Background: Infertility is the inability of a couple to conceive after one and a half years of
unprotected sex. Male infertility, which accounts for almost half of infertility cases, is …

OBJECTIVE: To examine whether a relationship exists between genetic polymorphisms of
glutathione S-transferase (GST) M1 and T1, CYP1A1∗ 2C, and male factor infertility …