A thermoreversible gelation polymer consisting of an aqueous solution in the sol state at
room temperature and in the gel state near body temperature was examined for its use in the …

A local drug delivery system based on sustained drug release is an attractive approach to
treat brain tumors. We have developed a novel device using drug-incorporated poly (lactic …

We have developed a drug-loaded poly (lactic-co-glycolic acid)(PLGA) microsphere-
containing thermoreversible gelation polymer (TGP)(drug/PLGA/TGP) formulation as a novel …

Background: The purpose of our study was to evaluate the application of thermoreversible
gelation polymer (TGP) as a local drug delivery system for malignant glioma. Materials and …

Many approaches to local tumor treatment have been reported and their efficacy
demonstrated in patients with malignant glioma. We studied thermoreversible gelation …

The novel nanoparticles (CPT-NP) were prepared by the solvent evaporation method using
methoxypolyethylene glycol–poly (dl-lactic acid) block copolymer as a matrix and …

This study investigated whether local delivery of 10-hydroxycamptothecin provides effective
inductive chemotherapy as assessed by significant tumor reduction. Established tumorigenic …

In this paper it is shown that when a thermosensitive hydrogel based on poly (N-
isopropylacrylamide)-poly (ethylene glycol)-poly (N-isopropylacrylamide)(pNIPAm-PEG …

Poly (D, L-lactic acid-co-glycolic acid)-b-poly (ethylene glycol)-b-poly (D, L-lactic acid-co-
glycolic acid)(PLGA–PEG–PLGA) hydrogels were tried as implants to encapsulate antitumor …

Camptothecin (CPT) and its water-insoluble derivatives are known as topoisomerase-I
inhibitors exhibiting high antitumoral activity against a wide spectrum of human …