The solubility of the hydrophobic drug ibuprofen has been compared in an aqueous solution
of polyamidoamine (PAMAM) G4 dendrimer and sodium dodecyl sulphate (SDS). The …

The aqueous solubility of non-steroidal anti-inflammatory drugs (NSAIDs) Ketoprofen,
Ibuprofen, Diflunisal and Naproxen were measured in the presence of the ethylenediamine …

Ketoprofen is a non-steroidal anti-inflammatory drug which is not freely soluble in water and
creates gastrointestinal problems. In the present study we investigated the potential of …

In the present study we investigated the effect of ethylenediamine (EDA) core
polyamidoamine (PAMAM) dendrimers on the aqueous solubility of nicotinic acid. The …

The aim of this study was to investigate the effect of low generation (G0–G3)
ethylenediamine (EDA) core poly (amidoamine)(PAMAM) dendrimers on the aqueous …

Dendrimers today are known for their three dimensional, monodispersed, highly branched,
macromolecular nano-scopic architecture with number of reactive end groups. Dendrimers …

Adequate aqueous solubility has been one of the desired properties while selecting drug
molecules and other bio-actives for product development. Often solubility of a drug …

The complexation of the practically insoluble drug furosemide (acidic pKa 3.22) with lower
generation PAMAM dendrimers showed a significant release dependence on the ionization …

Drug solubility could affect the therapeutic use of a drug because the biological activity of a
drug is only possible if some fraction of a dissolved drug can permeate and overcome …

Dendrimers are 3D, hyperbranched, tree-like polymers having immense potential in drug
delivery, targeting, diagnosis and as carriers for DNA/gene delivery. Dendrimers have …