Detection of Tumor‐Associated Neoangiogenesis by Doppler Ultrasonography During Early‐Stage Ovarian Cancer in Laying Hens: A Preclinical Model of Human …

A Barua, P Bitterman, JM Bahr… - … of Ultrasound in …, 2010 - Wiley Online Library
Objective. Tumor‐associated neoangiogenesis (TAN) is one of the earliest events in ovarian
tumor growth and represents a potential target for early detection of ovarian cancer (OVCA) …

VEGFR2-targeted ultrasound imaging agent enhances the detection of ovarian tumors at early stage in laying hens, a preclinical model of spontaneous ovarian …

A Barua, A Yellapa, JM Bahr, SA Machado… - Ultrasonic …, 2015 - journals.sagepub.com
Tumor-associated neoangiogenesis (TAN) is an early event in ovarian cancer (OVCA)
development. Increased expression of vascular endothelial growth factor receptor 2 …

Contrast‐Enhanced Sonography Depicts Spontaneous Ovarian Cancer at Early Stages in a Preclinical Animal Model

A Barua, P Bitterman, JM Bahr, S Basu… - … of Ultrasound in …, 2011 - Wiley Online Library
Objective Our goal was to examine the feasibility of using laying hens, a preclinical model of
human spontaneous ovarian cancer, in determining the kinetics of an ultrasound contrast …

[PDF][PDF] Enhancement of Ovarian Tumor Detection With> vA3 IntegrinYTargeted Ultrasound Molecular Imaging Agent in Laying Hens

A Barua, A Yellapa, JM Bahr, SA Machado - Int J Gynecol Cancer, 2014 - researchgate.net
Objective: Because of the lack of an effective early detection test, ovarian cancer (OVCA) in
most cases is detected at late stages and remains a fatal gynecological malignancy …

Detection of ovarian tumors in chicken by sonography: a step toward early diagnosis in humans?

A Barua, JS Abramowicz, JM Bahr… - … of Ultrasound in …, 2007 - Wiley Online Library
Objective Animal models of spontaneous ovarian cancer are important for understanding
early tumor development. Ovarian imaging may play an important role in following changes …

Molecular targeted imaging of vascular endothelial growth factor receptor (VEGFR)-2 and anti-NMP autoantibodies detect ovarian tumor at early stage

A Barua, T Qureshi, P Bitterman, JM Bahr, S Basu… - Cancer Research, 2012 - AACR
Background: Although several serum markers of ovarian cancer (OVCA) have been
suggested, none can detect OVCA at early stage specifically because of the lack of a …

Differences in the angiogenesis of benign and malignant ovarian tumors, demonstrated by analyses of color Doppler ultrasound, immunohistochemistry, and …

M Emoto, H Iwasaki, K Mimura… - … Journal of the …, 1997 - Wiley Online Library
BACKGROUND To clarify the differences in angiogenesis between benign and malignant
ovarian tumors, the authors examined the immunohistochemical characteristics and the …

A review of Doppler sonography for the assessment of tumour vascularity

S Ohlerth, B Kaser‐Hotz - Veterinary and comparative oncology, 2003 - Wiley Online Library
During the past decade, the vascular biology of cancer has become a highly interesting
research field. To assess tumour vascularity and perfusion, various strategies such as …

Transvaginal colour flow imaging in assessment of ovarian tumor neovascularization.

W Sawicki, B Spiewankiewicz… - European journal of …, 1997 - europepmc.org
Localization and intensity of angiogenesis in benign and malignant ovarian neoplasms
recorded by color Doppler transvaginal ultrasound has been assessed. Increased …

Ovarian cancer: applications of chickens to humans

A Barua, JM Bahr - Annual review of animal biosciences, 2022 - annualreviews.org
The lack of preclinical models of spontaneous ovarian cancer (OVCA), a fatal gynecological
malignancy, is a significant barrier to generating information on early changes indicative of …