Dendrimers for drug solubilization, dissolution and bioavailability
Solubility of a drug influences the behavior of compounds in biomedical applications. Poor
solubility of drugs and hydrophobicity along with other bioactive compounds limit their …
solubility of drugs and hydrophobicity along with other bioactive compounds limit their …
Dendrimer for solubility enhancement
A drug is effective in their molecular form; thus solubility in the biological fluid is important.
Pharmaceutical researchers are continuously working on the improvement of solubility of …
Pharmaceutical researchers are continuously working on the improvement of solubility of …
Dendrimers for enhanced drug solubilization
S Svenson, AS Chauhan - Nanomedicine, 2008 - Taylor & Francis
Approximately 40% of newly developed drugs are rejected by the pharmaceutical industry
and will never benefit a patient because of low water solubility. Another 17% of launched …
and will never benefit a patient because of low water solubility. Another 17% of launched …
Role of Dendrimer in Drug Solubilisation-A Review
RV Movliya, PM Patel - Drug Delivery Letters, 2019 - ingentaconnect.com
Objective: Dendrimers, a new class of synthetic polymers proved themselves very useful
tools for biomedical application due to their unique characteristics including water solubility …
tools for biomedical application due to their unique characteristics including water solubility …
Impact of dendrimers on solubility of hydrophobic drug molecules
Adequate aqueous solubility has been one of the desired properties while selecting drug
molecules and other bio-actives for product development. Often solubility of a drug …
molecules and other bio-actives for product development. Often solubility of a drug …
Dendrimers for enhanced drug solubilization
NK Jain, RK Tekade - Drug Delivery Strategies for Poorly Water …, 2013 - Wiley Online Library
Dendrimers are synthetic, absolutely branched, mono‐disperse, unimolecular micellar
architectures with nanometeric dimensions. They are compartmentalized structures with …
architectures with nanometeric dimensions. They are compartmentalized structures with …
The use of dendrimers to optimize the physicochemical and therapeutic properties of drugs
Dendrimers are increasingly being investigated as pharmaceutical delivery systems (Figs.
3.1 and 3.2) because of their ability to: improve the solubility and bioavailability of drugs; …
3.1 and 3.2) because of their ability to: improve the solubility and bioavailability of drugs; …
Dendrimers for drug delivery purposes
Currently, various types of nanocarriers have been widely used to deliver bioactive
compounds to improve the specificity/effectiveness of the active compound. Among these …
compounds to improve the specificity/effectiveness of the active compound. Among these …
Application of dendrimer–drug complexation in the enhancement of drug solubility and bioavailability
NK Jain, U Gupta - Expert opinion on drug metabolism & toxicology, 2008 - Taylor & Francis
Dendrimers are 3D, hyperbranched, tree-like polymers having immense potential in drug
delivery, targeting, diagnosis and as carriers for DNA/gene delivery. Dendrimers have …
delivery, targeting, diagnosis and as carriers for DNA/gene delivery. Dendrimers have …
[PDF][PDF] PAMAM Dendrimers mediated solubility enhancement of poorly soluble drugs: a concise review
High solubility, high permeability and good stability are basic prerequisites for achieving the
bioavailability and hence therapeutic effectiveness. Newly developed drugs having poor …
bioavailability and hence therapeutic effectiveness. Newly developed drugs having poor …