We investigated the effect of a monoclonal antibody against CD2 molecules (OX34) in
preventing the induction of experimental autoimmune myocarditis (EAM) induced by …

Autoimmune myocarditis is a T-cell-mediated autoimmune disease. CD4-positive T cells are
believed to be the most important for the initiation and mediation of the disease. This study …

We investigated the effects of anti‐αβ T cell receptor antibody in rat experimental
autoimmune myocarditis (HAM), using a new animal model of autoimmune myocarditis …

The heart is a target organ in several autoimmune diseases, and therefore it is important to
understand more about the effector cells involved in immune-mediated mechanisms of …

Experimental autoimmune myocarditis (EAM) is elicited in certain strains of mice by
immunizing with mouse cardiac myosin. Concomitant with the onset of myocardial …

Experimental induction of most autoimmune diseases appears to depend on the activation
of CD4+ T helper cells, while CD8+ lymphocytes may have a role in disease progression. To …

Experimental autoimmune myocarditis (EAM) resembles the lethal giant cell myocarditis
seen in humans, and the recurrent forms lead to dilated cardiomyopathy (DCM). EAM in rats …

BACKGROUND To elucidate the mechanisms of immune-related myocardial injuries, we
examined whether autoimmune myocarditis was passively transferable by use of humoral or …

We investigated the suppressive effects of immunoglobulin (Ig) on effector T cells in
autoimmune myocarditis. Treatment with Ig reduced production of the so-called T-helper …

Ag-specific activation of T lymphocytes requires two signals, one by the TCR and a second
by costimulatory molecules. In a CD4+ T helper cell-dependent experimental autoimmune …