Abstract [3 H] Paroxetine binding to human brain tissue was characterized. Competition
studies in the putamen and frontal cortex revealed single-site binding models for binding …

The characteristics of the binding of [3 H] paroxetine, a selective serotonin (5-HT) uptake
blocker, were investigated in human brain. The K d value was 0.23±0.07 nM, and the B max …

Serotonin transport in synapses and platelets is inhibited by tricyclic antidepressants as well
as by more selective transport inhibitors. This inhibition is hypothesized to be of importance …

The binding of the 5‐hydroxytryptamine (5‐HT, serotonin) uptake inhibitor [3H] paroxetine to
rat cortical homogenates has been characterized. The effect of tissue concentration was …

The dissociations of [3 H] imipramine,[3 H] paroxetine and [3 H] citalopram from the 5-HT
(serotonin 5-hydroxytryptamine) transporter were found to be markedly influenced by …

Citalopram binds with high affinity to a specific binding site located on the serotonin (5-HT)
transporter in 5-HT neurons. The binding affinity of [3 H] citalopram was found to increase …

Abstract Serotonin (5-hydroxytryptamine; 5HT) uptake sites have been measured using the
selective high affinity uptake inhibitor 3 H-citalopram in post-mortem frontal cortex from …

The sodium dependence of binding of [3H]]‐paroxetine, a selective serotonin uptake
inhibitor, to the serotonin transporter in rat diencephalon was studied in both brain …

The binding of [3H] paroxetine and [3H] ketanserin to particulate membranes from frontal
cortex of subjects who had or did not have schizophrenia was measured as was [3H] …

[3H] Paroxetine binding to particulate membrane from tissue, obtained at autopsy, from the
hippocampus, frontal cortex, and caudate nucleus from subjects who had or had not had …