Sepsis is a prevalent disease that has alarmingly high mortality rates and, for several
survivors, long-term morbidity. The modern definition of sepsis is an aberrant host response …

Neutrophil is a major player in the pathophysiology of severe sepsis. Recent studies have
revealed that the cell death mechanism of neutrophils directly relates to the development of …

Objective: Sepsis is defined as life-threatening organ dysfunction due to a dysregulated host
response to infection. In this article, we reviewed the correlation between neutrophil …

Sepsis, an overwhelming inflammatory response syndrome secondary to infection, is one of
the costliest and deadliest medical conditions worldwide. Neutrophils are classically …

Neutrophils are among the most abundant immune cells, representing about 50%− 70% of
all circulating leukocytes in humans. Neutrophils rapidly infiltrate inflamed tissues and play …

Delayed neutrophil apoptosis and overshooting neutrophil activity contribute to organ
dysfunction and subsequent organ failure in sepsis. Here, we investigated apoptotic …

Pyroptosis is a caspase-1 or caspase-4/5/11-dependent programmed cell death associated
with inflammation, which is initiated by inflammasomes or cytosolic LPS in innate immunity …

Sepsis develops when the initial host response is unable to contain the primary infection,
resulting in widespread inflammation and multiple organ dysfunction. The impairment of …

Sepsis remains a leading cause of death worldwide, despite advances in critical care, and
understanding of the pathophysiology and treatment strategies. No specific therapy or drugs …

Sepsis is a major health problem and a leading cause of death worldwide. In recent years, a
crescendo of attention has been directed to the mechanisms of cell death that develop …