Hepatic and peripheral T-lymphocyte patterns in patients with chronic hepatitis C infection: what correlation with histological activity?

A Perrella, O Perrella, C Sbreglia, P Conca… - International Journal …, 2001 - europepmc.org
The immunopathological processes involved in hepatic damage during chronic hepatitis C
infection are not fully understood. Several works suggest the role of T helper 1 (Th1) immune …

[PDF][PDF] Phenotypic and functional characterization of intrahepatic T lymphocytes during chronic hepatitis C

V Leroy, I Vigan, JF Mosnier, T Dufeu‐Duchesne… - …, 2003 - Wiley Online Library
The pathogenesis of liver cell injury during chronic hepatitis C (CHC) is poorly understood.
The cellular immune response is thought to play a key role in both inhibition of viral …

Peripheral lymphocyte subsets vary with stage of hepatitis C virus-associated liver disease.

K Morita, Y Fukuda, I Nakano, Y Katano… - Hepato …, 2005 - europepmc.org
Results Acute hepatitis patients had a high proportion of CD3+ T cells with increased CD4+
CD45RA-T helper and CD8+ CD11b-cytotoxic T cells. Compared to this group, chronic …

Liver‐infiltrating CD56 positive T lymphocytes in hepatitis C virus infection

K Yonekura, T Ichida, K Sato, S Yamagiwa, M Uchida… - Liver, 2000 - Wiley Online Library
Aim: Hepatitis C virus (HCV) is a major cause of post‐transfusional and sporadic hepatitis,
and leads to chronic liver disease. It has been suggested that virus‐specific cytotoxic T …

Liver‐infiltrating and circulating CD4+ T cells in chronic hepatitis C: immunodominant epitopes, HLA‐restriction and functional significance

HF Löhr, JF Schlaak, S Kollmannsperger, HP Dienes… - Liver, 1996 - Wiley Online Library
The aim was to assess the specificity and functional significance of liver‐infiltrating and
peripheral blood T cells in chronic hepatitis C. Peripheral blood mononuclear cells hepatitis …

Simultaneous evaluation of lymphocyte subpopulations in the liver and in peripheral blood mononuclear cells of HCV-infected patients: relationship with histological …

M Pernollet, E Jouvin-Marche, V Leroy… - Clinical & …, 2002 - academic.oup.com
Intrahepatic lymphocytes are believed to be involved in the immunopathogenesis of
hepatitis C virus (HCV) infection and the evolution of HCV-induced hepatitis. In the present …

Phenotypical analysis and cytokine release of liver‐infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiology

HF Löhr, JF Schlaak, G Gerken, B Fleischer, HP Dienes… - Liver, 1994 - Wiley Online Library
Cytokines released by infiltrating T cells may contribute to the hepatic injury in chronic
hepatitis. Therefore, we characterized peripheral blood‐and liver‐infiltrating T cells from …

Analysis of T cell repertoire in the liver of patients with chronic hepatitis C

T Umemura, K Yoshizawa, M Ota… - Clinical & …, 2000 - academic.oup.com
Many T cells infiltrate into the liver of patients with chronic hepatitis C (CH-C). They are
believed to play a crucial role in the immunopathogenesis of hepatic inflammation, but their …

Decrease in hepatic CD56+ T cells and Vα24+ natural killer T cells in chronic hepatitis C viral infection

T Deignan, MP Curry, DG Doherty, L Golden-Mason… - Journal of …, 2002 - Elsevier
Background/Aims: The intrahepatic immune system is likely to play a key role in determining
the outcome of hepatitis C virus (HCV) infection. The hepatic lymphocyte repertoire is …

T-lymphocyte subsets in peripheral blood and liver tissue of patients with chronic hepatitis B and C

D Dimitropoulou, M Karakantza, AC Tsamandas… - in vivo, 2011 - iv.iiarjournals.org
Aim: To evaluate the immune response in peripheral blood and liver tissue, through the
measurement of T-cell subsets, in patients with chronic hepatitis B (CHB) and C (CHC) …