Enterobactin: an archetype for microbial iron transport

KN Raymond, EA Dertz, SS Kim - Proceedings of the …, 2003 - National Acad Sciences
Bacteria have aggressive acquisition processes for iron, an essential nutrient. Siderophores
are small iron chelators that facilitate cellular iron transport. The siderophore enterobactin is …

Enzymatic hydrolysis of trilactone siderophores: where chiral recognition occurs in enterobactin and bacillibactin iron transport

RJ Abergel, AM Zawadzka, TM Hoette… - Journal of the …, 2009 - ACS Publications
Bacillibactin and enterobactin are hexadentate catecholate siderophores produced by
bacteria upon iron limitation to scavenge ferric ion and seem to be the ultimate siderophores …

Enterobactin Protonation and Iron Release:  Structural Characterization of the Salicylate Coordination Shift in Ferric Enterobactin1

RJ Abergel, JA Warner, DK Shuh… - Journal of the American …, 2006 - ACS Publications
The siderophore enterobactin (Ent) is produced by many species of enteric bacteria to
mediate iron uptake. This iron scavenger can be reincorporated by the bacteria as the ferric …

The Siderocalin/Enterobactin Interaction: A Link between Mammalian Immunity and Bacterial Iron Transport1

RJ Abergel, MC Clifton, JC Pizarro… - Journal of the …, 2008 - ACS Publications
The siderophore enterobactin (Ent) is produced by enteric bacteria to mediate iron uptake.
Ent scavenges iron and is taken up by the bacteria as the highly stable ferric complex [FeIII …

Enterobactin Protonation and Iron Release:  Hexadentate Tris-Salicylate Ligands as Models for Triprotonated Ferric Enterobactin1

SM Cohen, M Meyer, KN Raymond - Journal of the American …, 1998 - ACS Publications
Enterobactin mediates iron uptake in Escherichia coli and related bacteria. The structure of
the neutral protonated ferric enterobactin complex Fe [H3enterobactin] has been the source …

Selectivity of ferric enterobactin binding and cooperativity of transport in gram-negative bacteria

P Thulasiraman, SMC Newton, J Xu… - Journal of …, 1998 - Am Soc Microbiol
The ligand-gated outer membrane porin FepA serves Escherichia coli as the receptor for the
siderophore ferric enterobactin. We characterized the ability of seven analogs of …

[HTML][HTML] The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model

L Moynié, S Milenkovic, GLA Mislin, V Gasser… - Nature …, 2019 - nature.com
Bacteria use small molecules called siderophores to scavenge iron. Siderophore-Fe3+
complexes are recognised by outer-membrane transporters and imported into the periplasm …

Siderophore-Mediated Cargo Delivery to the Cytoplasm of Escherichia coli and Pseudomonas aeruginosa: Syntheses of Monofunctionalized Enterobactin Scaffolds …

T Zheng, JL Bullock, EM Nolan - Journal of the American …, 2012 - ACS Publications
The design and syntheses of monofunctionalized enterobactin (Ent, l-and d-isomers)
scaffolds where one catecholate moiety of enterobactin houses an alkene, aldehyde, or …

Export of the siderophore enterobactin in Escherichia coli: involvement of a 43 kDa membrane exporter

JL Furrer, DN Sanders, IG Hook‐Barnard… - Molecular …, 2002 - Wiley Online Library
The enterobactin system for iron transport in Escherichia coli is well characterized with the
exception of the mechanism of enterobactin secretion to the extracellular environment …

Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis product

DJ Raines, OV Moroz, EV Blagova… - Proceedings of the …, 2016 - National Acad Sciences
To acquire essential Fe (III), bacteria produce and secrete siderophores with high affinity
and selectivity for Fe (III) to mediate its uptake into the cell. Here, we show that the …