After a century of research into environmental mutagens and carcinogens, Where Do We Stand?

JD Vitorino, PM Costa - … Journal of Environmental Research and Public …, 2023 - mdpi.com
Cancer is one of the longest-known human diseases, yet only in recent times have we
begun to perceive that the percentage of neoplasms caused by environmental factors …

Improving prediction of chemical carcinogenicity by considering multiple mechanisms and applying toxicogenomic approaches

KZ Guyton, AD Kyle, J Aubrecht, VJ Cogliano… - … Research/Reviews in …, 2009 - Elsevier
While scientific knowledge of the potential health significance of chemical exposures has
grown, experimental methods for predicting the carcinogenicity of environmental agents …

Rethinking environmental carcinogenesis

M Kripke, JG Brody, E Hawk, AB Hernandez… - … Biomarkers & Prevention, 2020 - AACR
The 2010 report of the President's Cancer Panel concluded that the burden of cancer from
chemical exposures is substantial, while the programs for testing and regulation of …

Environmental carcinogenesis

J Higginson - Cancer, 1993 - Wiley Online Library
It generally is accepted that approximately 80% of all cancers have an environmental
component. However, although the cause and nature of certain human cancers are known …

Challenges to environmental toxicology and epidemiology: where do we stand and which way do we go?

B Pesch, T Brüning, R Frentzel-Beyme, G Johnen… - Toxicology letters, 2004 - Elsevier
Modern toxicology investigates a wide array of both old and new health hazards. Priority
setting is needed to select agents for research from the plethora of exposure circumstances …

Environmental carcinogenesis

T Sabo-Attwood, M Ramos-Nino… - Oncology: An Evidence …, 2006 - Springer
Environmental carcinogens are broadly defined as compounds that humans are exposed to
through diet, lifestyle, infectious agents, and occupation. They are considered as nongenetic …

Environmental carcinogenesis–100th anniversary of creating cancer

M Imai, O Hino - Cancer science, 2015 - Wiley Online Library
Asbestos is an environmental carcinogen, and asbestos‐related diseases represent a
global‐scale environmental issue. Mesothelioma is an aggressive, malignant tumor that …

Toxicogenomics and cancer susceptibility: advances with next-generation sequencing

B Ning, Z Su, N Mei, H Hong, H Deng… - … Science and Health …, 2014 - Taylor & Francis
The aim of this review is to comprehensively summarize the recent achievements in the field
of toxicogenomics and cancer research regarding genetic-environmental interactions in …

[图书][B] Chemical consequences: Environmental mutagens, scientist activism, and the rise of genetic toxicology

S Frickel - 2004 - books.google.com
Hereis the first historical and sociological account of the formation of an interdisciplinary
science known as genetic toxicology, and of the scientists' social movement that created it …

Developing sustainable studies on environmental health

RJ Albertini - … Research/Fundamental and Molecular Mechanisms of …, 2001 - Elsevier
Toxicogenetics, toxicogenomics and proteomics are providing new biomarkers for use in
human studies. These, coupled with the more traditional biological responses currently in …