We previously reported that MC32 cells resist carcinoembryonic antigen (CEA) DNA
vaccination by losing their antigen presentation to Ag-specific CTLs in the context of MHC …

Human colon cancers express carcinoembryonic antigen (CEA). Thus, CEA has been
considered as a potential vaccine target for immune therapy against colon cancer. In this …

Peripheral T-cell tolerance toward human carcinoembryonic self-antigen (CEA) was broken
in CEA-transgenic C57BL/6J mice by an oral CEA-based DNA vaccine. This vaccine …

This study describes a CD8+ T-cell line specific for a MHC class I-restricted
carcinoembryonic antigen (CEA) epitope, residues 526–533, isolated from CEA transgenic …

In this report, we have studied the immunogenicity of the nominal antigen, carcinoembryonic
antigen (CEA), and that of an anti-idiotype antibody, 3H1, which mimics CEA and can be …

In the present study, we have analysed the detailed cellular immune mechanisms involved
in tumour rejection in carcinoembryonic antigen (CEA) transgenic mice after immunization …

In order to develop immunotherapy strategies that are based on eliciting immune
responsiveness to the self-antigen, human carcinoembryonic antigen (CEA), we examined …

Induction of potent and sustained antitumor immunity depends on the efficient activation of
CD8+ and CD4+ T cells. Immunization using dendritic cells loaded with tumor antigens …

A lack of relevant animal models has hampered preclinical screening and critical evaluation
of the efficacy of human vaccines in vivo. Carcinoembryonic antigen–A2Kb (CEA–A2Kb) …

This study was designed to determine whether the vaccination of genetically modified
dendritic cells (DCs) simultaneously expressing carcinoembryonic antigen (CEA) …