The alleviation of oxidative stress is considered an effective treatment for acetaminophen
(APAP)-induced acute liver injury (AILI). However, it remains unknow whether the potential …

Aim Acetaminophen (APAP) overdose is the most frequent cause of drug-induced liver
damage. Magnolia officinalis is a traditional hepatoprotective Chinese medicine and …

Oxidative stress plays a crucial role in the pathogenesis of acute pancreatitis (AP).
Isoliquiritigenin (ISL) is a flavonoid monomer with confirmed antioxidant activity. However …

Context Rosmarinic acid (RA) dose-dependently ameliorates acetaminophen (APAP)
induced hepatotoxicity in rats. However, whether RA hepatoprotective effect is by regulating …

Isorhamnetin is a hepatoprotective flavonoid molecule derived from the leaves and fruits of
Hippophae rhamnoides L. However, the protective effect of isorhamnetin on acetaminophen …

Acetaminophen (APAP) overdose is a leading cause of drug-induced acute liver failure in
clinical and hospital settings. Fisetin (FST) is a phenolic compound derived from natural …

The hepatoprotective effect of Gypsophila elegans isoorientin (GEI) was evaluated using a
hepatic fibrosis model induced by CCl 4 in rats. The results revealed that GEI significantly …

Acute liver failure induced by acetaminophen (APAP) overdose is the main cause of drug-
induced liver injury (DILI). Caffeic acid (CA) is a phenolic compound from many natural …

Doxorubicin (DOX), which is used to treat cancer, has harmful effects that limit its therapeutic
application. Finding preventative agents to thwart DOX-caused injuries is thus imperative …

Acetaminophen (APAP) overdose can cause severe liver failure even death. Nearly half of
drug-induced liver injury is attributed to APAP in the US and many European countries …