Automated microfluidic compact disc (CD) cultivation system of Caenorhabditis elegans

N Kim, CM Dempsey, JV Zoval, JY Sze… - Sensors and actuators B …, 2007 - Elsevier
Microfabricated platforms for automated cultivation and behavioral observation of animals
would be a valuable tool in physiological and genetic studies. We report an automated …

NeuroChip: A Microfluidic Electrophysiological Device for Genetic and Chemical Biology Screening of Caenorhabditis elegans Adult and Larvae

C Hu, J Dillon, J Kearn, C Murray, V O'Connor… - Plos one, 2013 - journals.plos.org
Genetic and chemical biology screens of C. elegans have been of enormous benefit in
providing fundamental insight into neural function and neuroactive drugs. Recently the …

An automated microfluidic system for screening Caenorhabditis elegans behaviors using electrotaxis

D Liu, B Gupta, PR Selvaganapathy - Biomicrofluidics, 2016 - pubs.aip.org
Caenorhabditis elegans (C. elegans) is a widely used animal model to study mechanisms of
biological processes and human diseases. To facilitate manipulations of C. elegans in the …

Microfluidic laboratories for C. elegans enhance fundamental studies in biology

NA Bakhtina, JG Korvink - Rsc Advances, 2014 - pubs.rsc.org
The in vivo analysis of a small multicellular organism such as the nematode Caenorhabditis
elegans, enables fundamental biomedical and environmental studies of a complete …

Neuroscience research using small animals on a chip: from nematodes to zebrafish larvae

P Bansal, A Abraham, J Garg, EE Jung - BioChip Journal, 2021 - Springer
Implementation of microfluidic technology to study small animal models such as
Caenorhabditis elegans worms (soil-dwelling nematodes), Drosophila melanogaster (fruit …

A microfluidic diode for sorting and immobilization of Caenorhabditis elegans

L Yang, T Hong, Y Zhang, JGS Arriola, BL Nelms… - Biomedical …, 2017 - Springer
Caenorhabditis elegans (C. elegans) is a powerful model organism extensively used in
studies of human aging and diseases. Despite the numerous advantages of C. elegans as a …

Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

HB Atakan, R Xiang, M Cornaglia, L Mouchiroud… - Scientific reports, 2019 - nature.com
The nematode Caenorhabditis elegans is a suitable model organism in drug screening.
Traditionally worms are grown on agar plates, posing many challenges for long-term culture …

A microfabricated array of clamps for immobilizing and imaging C. elegans

SE Hulme, SS Shevkoplyas, J Apfeld, W Fontana… - Lab on a Chip, 2007 - pubs.rsc.org
This paper describes the fabrication of a microfluidic device for rapid immobilization of large
numbers of live C. elegans for performing morphological analysis, microsurgery, and …

Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans

N Chronis, M Zimmer, CI Bargmann - Nature methods, 2007 - nature.com
The nematode C. elegans is an excellent model organism for studying behavior at the
neuronal level. Because of the organism's small size, it is challenging to deliver stimuli to C …

Development of an integrated microfluidic device for evaluating of in vivo chemo-sensing of intact Caenorhabditis elegans

J Wang, Z Li, Z Xu, L Hu, X Feng, M Chen, W Du… - Sensors and Actuators B …, 2013 - Elsevier
Conventional macro-scale methods are not appropriate for in vivo neuronal analysis at a
single neuron level when experimental subject is small model organism Caenorhabditis …