Droplet array for screening acute behaviour response to chemicals in Caenorhabditis elegans
Caenorhabditis elegans is an excellent model organism for studying chemosensation as a
significant part of its nervous system and genome are devoted to the detection of chemical …
significant part of its nervous system and genome are devoted to the detection of chemical …
Advances in C. áelegans behavior research with microfluidic devices and its future prospects in the evaluation of exogenous pollutants
The nematode Caenorhabditis elegans (C. áelegans) is characterized by small size, a
transparent body, and a simple structure. However, traditional techniques (eg, sorting and …
transparent body, and a simple structure. However, traditional techniques (eg, sorting and …
Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans
M Cornaglia, T Lehnert, MAM Gijs - Lab on a Chip, 2017 - pubs.rsc.org
In a typical high-throughput drug screening (HTS) process, up to millions of chemical
compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit …
compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit …
Microfluidic tools for developmental studies of small model organisms–nematodes, fruit flies, and zebrafish
Studying the genetics of development with small model organisms such as the zebrafish
(Danio Rerio), the fruit fly (Drosophila melanogaster), and the soil‐dwelling nematode …
(Danio Rerio), the fruit fly (Drosophila melanogaster), and the soil‐dwelling nematode …
Droplet-based microfluidic system for individual Caenorhabditis elegans assay
A droplet-based microfluidic system integrating a droplet generator and a droplet trap array
is described for encapsulating individual Caenorhabditis elegans into a parallel series of …
is described for encapsulating individual Caenorhabditis elegans into a parallel series of …
[HTML][HTML] Microfluidic Device for Microinjection of Caenorhabditis elegans
Microinjection is an established and reliable method to deliver transgenic constructs and
other reagents to specific locations in C. elegans worms. Specifically, microinjection of a …
other reagents to specific locations in C. elegans worms. Specifically, microinjection of a …
Droplet microfluidics for characterizing the neurotoxin-induced responses in individual Caenorhabditis elegans
A droplet-based microfluidic device integrated with a novel floatage-based trap array and a
tapered immobilization channel array was presented for characterizing the neurotoxin …
tapered immobilization channel array was presented for characterizing the neurotoxin …
[HTML][HTML] A programmable microvalve-based microfluidic array for characterization of neurotoxin-induced responses of individual C. elegans
The soil dwelling nematode Caenorhabditis elegans (C. elegans) is an excellent model
organism for the study of numerous disease including neurodegenerative disease. In this …
organism for the study of numerous disease including neurodegenerative disease. In this …
C. elegans in high-throughput drug discovery
LP O'Reilly, CJ Luke, DH Perlmutter… - Advanced drug delivery …, 2014 - Elsevier
Caenorhabditis elegans has been proven to be a useful model organism for investigating
molecular and cellular aspects of numerous human diseases. More recently, investigators …
molecular and cellular aspects of numerous human diseases. More recently, investigators …
Microfluidic platform with spatiotemporally controlled micro-environment for studying long-term C. elegans developmental arrests
Animals' long-term survival is dependent on their ability to sense, filter and respond to their
environment at multiple timescales. For example, during development, animals integrate …
environment at multiple timescales. For example, during development, animals integrate …