Microfluidics-enabled method to identify modes of Caenorhabditis elegans paralysis in four anthelmintics

R Lycke, A Parashar, S Pandey - Biomicrofluidics, 2013 - pubs.aip.org
The discovery of new drugs is often propelled by the increasing resistance of parasites to
existing drugs and the availability of better technology platforms. The area of microfluidics …

The Egg-Counter: A novel microfluidic platform for characterization of Caenorhabditis elegans egg-laying

SA Banse, CM Jarrett, KJ Robinson, BW Blue… - Lab on a Chip, 2024 - pubs.rsc.org
Reproduction is a fundamental process that shapes the demography of every living
organism yet is often difficult to assess with high precision in animals that produce large …

Enhanced Caenorhabditis elegans Locomotion in a Structured Microfluidic Environment

S Park, H Hwang, SW Nam, F Martinez, RH Austin… - PloS one, 2008 - journals.plos.org
Background Behavioral studies of Caenorhabditis elegans traditionally are done on the
smooth surface of agar plates, but the natural habitat of C. elegans and other nematodes is …

Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans

SE Hulme, SS Shevkoplyas, AP McGuigan, J Apfeld… - Lab on a Chip, 2010 - pubs.rsc.org
This article describes the fabrication of a microfluidic device for the liquid culture of many
individual nematode worms (Caenorhabditis elegans) in separate chambers. Each chamber …

A simple method for high throughput chemical screening in Caenorhabditis elegans

M Lucanic, T Garrett, MS Gill, GJ Lithgow - JoVE (Journal of Visualized …, 2018 - jove.com
Caenorhabditis elegans is a useful organism for testing chemical effects on physiology.
Whole organism small molecule screens offer significant advantages for identifying …

Versatile size-dependent sorting of C. elegans nematodes and embryos using a tunable microfluidic filter structure

L Dong, M Cornaglia, T Lehnert, MAM Gijs - Lab on a Chip, 2016 - pubs.rsc.org
The roundworm Caenorhabditis elegans (C. elegans) is a powerful model organism for
addressing fundamental biological questions related to human disease and aging. Its life …

An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging

M Cornaglia, L Mouchiroud, A Marette, S Narasimhan… - Scientific reports, 2015 - nature.com
Studies of the real-time dynamics of embryonic development require a gentle embryo
handling method, the possibility of long-term live imaging during the complete …

Parallel-Channel Electrotaxis and Neuron Screening of Caenorhabditis elegans

K Youssef, D Archonta, T Kubiseski, A Tandon, P Rezai - Micromachines, 2020 - mdpi.com
In this paper, we report a novel microfluidic method to conduct a Caenorhabditis elegans
electrotaxis movement assay and neuronal imaging on up to 16 worms in parallel. C …

[图书][B] C. elegans

D Biron, G Haspel - 2015 - Springer
Tractable models such as the nematode Caenorhabditis elegans provide profound insight
into a wide range of biological phenomena. It is the objective of any scientific effort to …

[HTML][HTML] ChIP and Chips: Introducing the WormPharm for correlative studies employing pharmacology and genome-wide analyses in C. elegans

JH Doh, AB Moore, İ Çelen, MT Moore… - Journal of Biological …, 2016 - ncbi.nlm.nih.gov
We present the WormPharm, an automated microfluidic platform that utilizes an axenic
medium to culture C. elegans. The WormPharm is capable of sustaining C. elegans for …