Most visual screens based on fluorescent markers are currently limited in throughput and
accuracy. Here we present the first genetic screen of a mutagenized population of C …

Abstract Background The nematode Caenorhabditis elegans is widely used as a model for
understanding the neuronal and genetic bases of behavior. Recent studies have required …

Micro fabricated fluidic devices provide an accessible micro-environment for in vivo studies
on small organisms. Simple fabrication processes are available for microfluidic devices …

Microfluidic devices have been developed for imaging behavior and various cellular
processes in Caenorhabditis elegans, but not subcellular processes requiring high spatial …

Animal response to changes in environmental cues is a complex dynamical process that
occurs at diverse molecular and cellular levels. To gain a quantitative understanding of such …

Lifespan is a biological process regulated by several genetic pathways. One strategy to
investigate the biology of aging is to study animals that harbor mutations in components of …

The nematode (worm) C. elegans is a leading multicellular animal model to study neuronal-
basis of behavior. Worms respond to a wide range of stimuli and exhibit characteristic …

C. elegans-based assays require age-synchronized populations prior to experimentation to
achieve standardized sets of worm populations, due to which age-induced heterogeneous …

Culturing Caenorhabditis elegans (C. elegans) in a large-scale manner on agar plates can
be time-consuming and difficult. This protocol describes a simple and inexpensive method to …

The nematode Caenorhabditis elegans (C. elegans) receives attention as a bioindicator,
and the C. elegans condition has been recently analyzed using microfluidic devices …