This paper describes the DNA sequence analysis of 729 independent spontaneous lacI−
mutation This total is comprised of 478 novel mutations and 251 previously described …

We have obtained via DNA sequence analysis a spectrum of 174 spontaneous mutations
occurring in the lacI gene of Escherichia coli. The spectrum comprised base substitution …

To gain more detailed insight into the nature and mechanisms of spontaneous mutations, we
undertook a DNA sequence analysis of a large collection of spontaneous mutations in the N …

The last few years have given us new fundamental insights into the mechanisms of
mutagenesis in bacteria, particularly Escherichia coli. The existence of a non …

Mutational spectra produced by mutagens in various repair backgrounds can provide
important information about the roles of different repair systems in the mutagenic process …

Spontaneous forward mutation in lacI was analyzed by DNA sequencing in a Dut− strain of
E. coli. Hyperuracil incorporation into DNA due to the defect in deoxyuridinetriphosphatase …

Mutation frequency decline (MFD) is an irreversible loss of newly-induced suppressor
mutations occurring in excision-proficient Escherichia coli during a short period of incubation …

To determine whether base-to-base variations in the rate of excision repair influence the
distribution of mutations, we have developed a method to measure UV photoproducts at …

Whereas in the past we had to be content with mutation induction and survival curves, the
recently developed technologies permitting the rapid cloning and sequencing of mutant …

Dose-response curves were compared for deletions [ColB R (resistant to colicin B)
mutations being more than 80% deletions] and base changes (reversion of argF am to …