Fifteen‐year quest for microphthalmia‐associated transcription factor target genes

Y Cheli, M Ohanna, R Ballotti… - Pigment cell & …, 2010 - Wiley Online Library
Microphthalmia‐associated transcription factor (MITF) was initially shown to play a key role
in melanocyte differentiation through the direct transcriptional control of TYROSINASE …

[HTML][HTML] The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology

A Kawakami, DE Fisher - Laboratory investigation, 2017 - Elsevier
Certain transcription factors have vital roles in lineage development, including specification
of cell types and control of differentiation. Microphthalmia-associated transcription factor …

Identification of a novel isoform of microphthalmia-associated transcription factor that is enriched in retinal pigment epithelium

S Amae, N Fuse, K Yasumoto, S Sato, I Yajima… - Biochemical and …, 1998 - Elsevier
Mutations at the mouse locus encoding microphthalmia-associated transcription factor (Mitf)
affect the development of many cell types, including retinal pigment epithelium (RPE) …

A big gene linked to small eyes encodes multiple Mitf isoforms: many promoters make light work

KENI YASUMOTO, S Amae, T Udono… - Pigment cell …, 1998 - Wiley Online Library
Among more than 80 different loci related to mouse coat color, microphthalmia‐associated
transcription factor (Mitf) encoded at the mouse microphthalmia locus is one of the most …

Regulation of melanocyte pivotal transcription factor MITF by some other transcription factors

P Wan, Y Hu, L He - Molecular and cellular biochemistry, 2011 - Springer
The microphthalmia transcription factor (MITF) is discussed as the master gene for
melanocytic survival and a key transcription factor regulating the expression of tyrosinase …

Melanocytes and the Microphthalmia Transcription Factor Network

E Steingrímsson, NG Copeland, NA Jenkins - Annu. Rev. Genet., 2004 - annualreviews.org
▪ Abstract The first mouse microphthalmia transcription factor (Mitf) mutation was discovered
over 60 years ago, and since then over 24 spontaneous and induced mutations have been …

MITF: master regulator of melanocyte development and melanoma oncogene

C Levy, M Khaled, DE Fisher - Trends in molecular medicine, 2006 - cell.com
Microphthalmia-associated transcription factor (MITF) acts as a master regulator of
melanocyte development, function and survival by modulating various differentiation and …

MITF—the first 25 years

CR Goding, H Arnheiter - Genes & development, 2019 - genesdev.cshlp.org
All transcription factors are equal, but some are more equal than others. In the 25 yr since
the gene encoding the microphthalmia-associated transcription factor (MITF) was first …

[HTML][HTML] Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation

S Shibahara, K Takeda, K Yasumoto, T Udono… - Journal of Investigative …, 2001 - Elsevier
Microphthalmia-associated transcription factor (MITF) regulates the differentiation and
development of melanocytes and retinal pigment epithelium and is also responsible for …

Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations

K Takeda, K Yasumoto, N Kawaguchi, T Udono… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Microphthalmia-associated transcription factor (Mitf) regulates the differentiation of
melanocytes, optic cup-derived retinal pigment epithelium (RPE), and some types of bone …