Background Complicated urinary tract infections (cUTIs) are responsible for a major share of
all antibiotic consumption in hospitals. We aim to describe risk factors for treatment failure …

ABSTRACT Introduction: Urinary tract infections (UTIs) are the most common healthcare-
acquired infections, and are associated with high morbidity and mortality. Worldwide use of …

Background Uncomplicated urinary tract infections (UTIs) are amongst the most frequent
infections presenting in the outpatient setting. A growing number of clinical trials are …

Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae pose a huge threat
to human health, especially in the context of complicated urinary tract infections (cUTIs) …

Overuse of carbapenems has led to the increasing carbapenem-resistant
Enterobacteriaceae. It is still unknown whether other antibiotics especially novel β-lactam/β …

Background Tebipenem pivoxil hydrobromide (TBP-PI-HBr) is an orally bioavailable prodrug
that is rapidly converted in plasma to the carbapenem, tebipenem. Tebipenem has in vitro …

The prospective, multicenter, double-blind study presented in this report evaluated whether
or not intravenous (IV) administration of doripenem, a carbapenem with bactericidal activity …

Objective: The goal of the present study was to evaluate treatment with Canephron®
compared to standard antibiotic treatment after diagnosis of acute cystitis or urinary tract …

Background Data are limited regarding use of piperacillin/tazobactam for ESBL urinary tract
infections (UTIs). The objective of this study was to compare clinical outcomes of patients …

Purpose Fosfomycin has been used more frequently in managing uncomplicated urinary
tract infections (UTIs) due to decreased compliance and increased multidrug-resistant …