[HTML][HTML] Glycosylation of cancer extracellular vesicles: capture strategies, functional roles and potential clinical applications
ÁM Martins, CC Ramos, D Freitas, CA Reis - Cells, 2021 - mdpi.com
Glycans are major constituents of extracellular vesicles (EVs). Alterations in the
glycosylation pathway are a common feature of cancer cells, which gives rise to de novo or …
glycosylation pathway are a common feature of cancer cells, which gives rise to de novo or …
Glycoconjugates from extracellular vesicles: Structures, functions and emerging potential as cancer biomarkers
J Costa - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2017 - Elsevier
Extracellular vesicles (EVs) are released by virtually all cells, carry cellular molecules to the
extracellular environment, and may interact with other cells. They are found in body fluids …
extracellular environment, and may interact with other cells. They are found in body fluids …
Different isolation approaches lead to diverse glycosylated extracellular vesicle populations
D Freitas, M Balmaña, J Poças, D Campos… - Journal of …, 2019 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous group of small secreted particles involved
in intercellular communication and mediating a broad spectrum of biological functions. EVs …
in intercellular communication and mediating a broad spectrum of biological functions. EVs …
Altered biodistribution of deglycosylated extracellular vesicles through enhanced cellular uptake
Extracellular vesicles (EVs) from cancer are delivered both proximal and distal organs. EVs
are highly glycosylated at the surface where EVs interact with cells and therefore has an …
are highly glycosylated at the surface where EVs interact with cells and therefore has an …
Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives
It is now acknowledged that extracellular vesicles (EVs) are important effectors in a vast
number of biological processes through intercellular transfer of biomolecules. Increasing …
number of biological processes through intercellular transfer of biomolecules. Increasing …
Extracellular vesicles in cancer therapy
SE Wang - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), including a variety of membrane-enclosed nanosized particles
carrying cell-derived cargo, mediate a major type of intercellular communication in …
carrying cell-derived cargo, mediate a major type of intercellular communication in …
[HTML][HTML] Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications
V Vrablova, N Kosutova, A Blsakova, A Bertokova… - Biotechnology …, 2023 - Elsevier
This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …
[HTML][HTML] Extracellular vesicles from ovarian carcinoma cells display specific glycosignatures
Cells release vesicles to the extracellular environment with characteristic nucleic acid,
protein, lipid, and glycan composition. Here we have isolated and characterized …
protein, lipid, and glycan composition. Here we have isolated and characterized …
[HTML][HTML] Intercellular vesicular transfer by exosomes, microparticles and oncosomes-implications for cancer biology and treatments
Intercellular communication is a normal feature of most physiological interactions between
cells in healthy organisms. While cells communicate directly through intimate physiology …
cells in healthy organisms. While cells communicate directly through intimate physiology …
Extracellular vesicles as natural therapeutic agents and innate drug delivery systems for cancer treatment: Recent advances, current obstacles, and challenges for …
As cancer poses a significant threat to the well-being of humans on a global scale, many
researchers have embarked on the search for effective anticancer therapeutic agents. In …
researchers have embarked on the search for effective anticancer therapeutic agents. In …