Marfan syndrome is a multisystem connective tissue disorder usually associated with
mutation in fibrillin, and occasionally with mutation in TGFBR1 or 2. The clinical diagnosis is …

Pregnancy in women with Marfan syndrome (MFS) presents challenges to the clinician and
the patient due to the increased incidence of maternal complications and involvement of the …

Marfan's syndrome is an heritable, generalized connective tissue disorder, clinically
manifest by abnormalities of the eye, the skeletal system, and the cardiovascular system …

One of the most common inherited disorders of connective tissue, Marfan syndrome (MFS,
MIM# 154700) is a predominantly autosomal dominant condition with a reported incidence …

A 32-year-old woman with Marfan syndrome and an 8.1 cm aortic root with moderate aortic
regurgitation reported she was pregnant. She had refused previous surgery but agreed to …

Background The risk of aortic complications associated with pregnancy in women with
Marfan syndrome (MFS) is not fully understood. Methods and Results MFS women …

Pregnancy poses a threat to women with aortopathy. Conclusive data on the obstetric and
aortic outcome in this risk collective, especially when it comes to aortic complications in the …

Combating a little known disease The Marfan syndrome is generally thought to be rare, but
clinicians who have seen how the gene expression can shade into normality in affected …

Aortic disease is the main cause of death among patients with Marfan syndrome. Before the
development of open surgery, most patients died in the fourth decade of life. Improvements …

Purpose This study aimed to develop objective diagnostic criteria for early onset Marfan
syndrome (eoMFS) to facilitate early diagnosis and timely interventions. Methods On the …