Clinical efficacy and safety of novel antibiotics for complicated urinary tract infection: A systematic review and meta-analysis of randomized controlled trials

KC Hung, WW Tsai, CW Hsu, CC Lai, HJ Tang… - International Journal of …, 2023 - Elsevier
Objective To assess the clinical efficacy and safety of novel antibiotics for complicated
urinary tract infections (cUTIs). Methods Three electronic databases (Medline, Embase and …

Efficacy and safety of carbapenems vs new antibiotics for treatment of adult patients with complicated urinary tract infections: a systematic review and meta-analysis

Y Ezure, V Rico, DL Paterson, L Hall… - Open Forum …, 2022 - academic.oup.com
This systematic review and meta-analysis evaluated the clinical efficacy and safety of
carbapenems for the treatment of complicated urinary tract infections (cUTIs), with the …

A review of recent advances in the treatment of adults with complicated urinary tract infection

E Rando, F Giovannenze, R Murri… - Expert Review of Clinical …, 2022 - Taylor & Francis
Introduction Complicated urinary tract infections (cUTIs) entail diverse clinical conditions that
could be managed differently and not necessarily with premature empiric therapy. Since …

Carbapenems vs alternative antibiotics for the treatment of complicated urinary tract infection: A systematic review and network meta-analysis

X Tan, Q Pan, C Mo, X Li, X Liang, Y Li, Y Lan, L Chen - Medicine, 2020 - journals.lww.com
Background: Complicated urinary tract infections (cUTI) are universal reasons for
hospitalization, and highly likely to develop into sepsis or septic shock. Carbapenem …

Antibiotics efficacy in clinical and microbiological cure of uncomplicated urinary tract infection: a systematic review and network meta-analysis

MF Hadidi, N Alhamami, M Alhakami… - World Journal of …, 2024 - Springer
Purpose Fosfomycin has been used more frequently in managing uncomplicated urinary
tract infections (UTIs) due to decreased compliance and increased multidrug-resistant …

Efficacy of carbapenems versus alternative antimicrobials for treating complicated urinary tract infections caused by antimicrobial-resistant Gram-negative bacteria …

M Maeda, T Hasegawa, H Noma, E Ota - BMJ open, 2023 - bmjopen.bmj.com
Introduction Complicated urinary tract infections (cUTIs) are associated with poor prognosis.
The widespread infection of multidrug-resistant Gram-negative uropathogens such as …

An update on emerging therapies for urinary tract infections

A Majeed, S Alarfaj, R Darouiche… - Expert Opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Urinary tract infections (UTIs) are the most common healthcare-
acquired infections, and are associated with high morbidity and mortality. Worldwide use of …

Emerging drugs for bacterial urinary tract infections

FME Wagenlehner, W Weidner… - Expert Opinion on …, 2005 - Taylor & Francis
Bacterial urinary tract infections (UTIs) are frequent infections in the outpatient as well as in
the nosocomial setting. The stratification into uncomplicated and complicated UTIs has …

Comparative effectiveness of antibiotics for uncomplicated urinary tract infections: network meta-analysis of randomized trials

BJ Knottnerus, L Grigoryan, SE Geerlings… - Family …, 2012 - academic.oup.com
Background The efficacies and adverse effects of different antibiotics for uncomplicated
urinary tract infections (UTIs) have been studied by standard meta-analytic methods using …

Novel antibiotics in the treatment of urinary tract infections

KG Naber, FME Wagenlehner - European Urology Focus, 2019 - Elsevier
Conclusions Several new antibiotic agents are currently close to being marketed or are in
the late clinical phase of development. However, unique novel compounds are rare, so …