Background Unlike other human tumors, gastric cancer remains a great therapeutic
challenge since no standardized postoperative treatment exists. Knowledge of molecular …

Background In gastric cancer, the recurrence rate is high even after curative surgery. A
relevant issue is the identification of independent prognostic factors to select high‐risk …

Purpose Vascular endothelial growth factor (VEGF)-D and its homolog VEGF-C influence
lymphangiogenesis through activation of VEGF receptor 3 (VEGFR-3), and have been …

Background Many studies have shown that angiogenesis plays an important role in the
process of cancer development and progression. Vascular endothelial growth factor (VEGF) …

Abstract Background and Objectives: Angiogenic factors play a major role in tumor growth
and metastasis. The purpose of this study was to clarify the prognostic significance of the …

The aim of this study was to analyse the impact of epidermal growth factor receptor (EGFR),
thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), thymidine …

BACKGROUND Recently many studies have demonstrated that the degree of tumor
angiogenesis is related to the aggressiveness of the tumor and clinical outcome. Vascular …

Background Hypoxia influences tumor growth by inducing angiogenesis and genetic
alterations. Hypoxia-inducible factor 1α (HIF-1α), p53, and vascular endothelial growth factor …

Background: It has recently been reported that the microvessel density in a tumor correlates
with hematogenous metastasis in gastric carcinoma. The aim of this study was to evaluate …

This study was undertaken to determine the value of tumour microvessel density (MVD) and
the expression of p53 and vascular endothelial growth factor (VEGF) as prognostic markers …