The roles of microphthalmia-associated transcription factor and pigmentation in melanoma
JJ Hsiao, DE Fisher - Archives of biochemistry and biophysics, 2014 - Elsevier
MITF and pigmentation play important roles in both normal melanocyte and transformed
melanoma cell biology. MITF is regulated by many pathways and it also regulates many …
melanoma cell biology. MITF is regulated by many pathways and it also regulates many …
Frequent mutations in the MITF pathway in melanoma
JC Cronin, J Wunderlich, SK Loftus… - Pigment cell & …, 2009 - Wiley Online Library
Microphthalmia‐associated transcription factor (MITF) is involved in melanocyte cell
development, pigmentation and neoplasia. To determine whether MITF is somatically …
development, pigmentation and neoplasia. To determine whether MITF is somatically …
MITF: master regulator of melanocyte development and melanoma oncogene
C Levy, M Khaled, DE Fisher - Trends in molecular medicine, 2006 - cell.com
Microphthalmia-associated transcription factor (MITF) acts as a master regulator of
melanocyte development, function and survival by modulating various differentiation and …
melanocyte development, function and survival by modulating various differentiation and …
Microphthalmia‐associated transcription factor (MITF) is required but is not sufficient to induce the expression of melanogenic genes
C Gaggioli, R Buscà, P Abbe, JP Ortonne… - Pigment cell …, 2003 - Wiley Online Library
Microphthalmia‐associated transcription factor (MITF) plays a pivotal role in melanocyte
survival and differentiation. Nevertheless, until now it has not been possible to show that …
survival and differentiation. Nevertheless, until now it has not been possible to show that …
The melanocyte-specific isoform of the microphthalmia transcription factor affects the phenotype of human melanoma
E Selzer, V Wacheck, T Lucas, E Heere-Ress, M Wu… - Cancer research, 2002 - AACR
The microphthalmia transcription factor MITF plays a pivotal role in the development and
differentiation of melanocytes. The purpose of this work was to investigate the expression …
differentiation of melanocytes. The purpose of this work was to investigate the expression …
Regulation of pigment cell‐specific gene expression by MITF
S Shibahara, KENI YASUMOTO, S Amae… - Pigment Cell …, 2000 - Wiley Online Library
Melanocyte and retinal pigment epithelium (RPE) specifically express tyrosinase and other
melanin‐producing enzymes. Microphthalmia‐associated transcription factor (Mitf), encoded …
melanin‐producing enzymes. Microphthalmia‐associated transcription factor (Mitf), encoded …
[HTML][HTML] The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology
A Kawakami, DE Fisher - Laboratory investigation, 2017 - Elsevier
Certain transcription factors have vital roles in lineage development, including specification
of cell types and control of differentiation. Microphthalmia-associated transcription factor …
of cell types and control of differentiation. Microphthalmia-associated transcription factor …
A germline oncogenic MITF mutation and tumor susceptibility
B Bressac-de Paillerets, F Lesueur… - European journal of cell …, 2014 - Elsevier
MITF (Microphthalmia-associated transcription factor) is a lineage specific transcription
factor that plays a critical role in melanocyte homeostasis and whose deregulation has been …
factor that plays a critical role in melanocyte homeostasis and whose deregulation has been …
[HTML][HTML] MITF in normal melanocytes, cutaneous and uveal melanoma: a delicate balance
MC Gelmi, LE Houtzagers, T Strub, I Krossa… - International journal of …, 2022 - mdpi.com
Microphthalmia-associated transcription factor (MITF) is an important regulator of
melanogenesis and melanocyte development. Although it has been studied extensively in …
melanogenesis and melanocyte development. Although it has been studied extensively in …
[HTML][HTML] MITF in melanoma: mechanisms behind its expression and activity
ML Hartman, M Czyz - Cellular and Molecular Life Sciences, 2015 - Springer
MITF (microphthalmia-associated transcription factor) represents a melanocytic lineage-
specific transcription factor whose role is profoundly extended in malignant melanoma. Over …
specific transcription factor whose role is profoundly extended in malignant melanoma. Over …