The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis

L Larribere, C Hilmi, M Khaled, C Gaggioli… - Genes & …, 2005 - genesdev.cshlp.org
Microphthalmia-associated transcription factor (MITF) M-form is a melanocyte-specific
transcription factor that plays a key role in melanocyte development, survival, and …

Expression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and …

MJ Pierrat, V Marsaud, A Mauviel… - Journal of Biological …, 2012 - ASBMB
The melanocyte-specific transcription factor M-MITF is involved in numerous aspects of
melanoblast lineage biology including pigmentation, survival, and migration. It plays …

Activation of the Mitf promoter by lipid‐stimulated activation of p38‐stress signalling to CREB

B Saha, SK Singh, C Sarkar, R Bera… - Pigment cell …, 2006 - Wiley Online Library
The microphthalmia‐associated transcription factor Mitf plays a critical role in regulating
many aspects of melanocyte biology. It is required for melanoblast and postnatal melanocyte …

MITF reprograms the extracellular matrix and focal adhesion in melanoma

R Dilshat, V Fock, C Kenny, I Gerritsen, RMJ Lasseur… - Elife, 2021 - elifesciences.org
The microphthalmia-associated transcription factor (MITF) is a critical regulator of
melanocyte development and differentiation. It also plays an important role in melanoma …

Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations

K Takeda, K Yasumoto, N Kawaguchi, T Udono… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Microphthalmia-associated transcription factor (Mitf) regulates the differentiation of
melanocytes, optic cup-derived retinal pigment epithelium (RPE), and some types of bone …

Regulation of melanocyte pivotal transcription factor MITF by some other transcription factors

P Wan, Y Hu, L He - Molecular and cellular biochemistry, 2011 - Springer
The microphthalmia transcription factor (MITF) is discussed as the master gene for
melanocytic survival and a key transcription factor regulating the expression of tyrosinase …

Microphthalmia-associated transcription factor gene amplification in metastatic melanoma is a prognostic marker for patient survival, but not a predictive marker for …

S Ugurel, R Houben, D Schrama, H Voigt… - Clinical cancer …, 2007 - AACR
Purpose: The microphthalmia-associated transcription factor (MITF) is regarded as a key
oncogene of the melanocytic lineage since it was detected by a genome-wide analysis to be …

Transcriptional Activation of the Melanocyte-Specific Genes by the Human Homolog of the Mouse Microphthalmia Protein

K Yasumoto, H Mahalingam, H Suzuki… - The journal of …, 1995 - academic.oup.com
Mi protein encoded at the mouse microphthalmia (mi) locus is a transcription factor with a
basic helix-loop-helix/leucine zipper structure. To assess the function of the human homolog …

“Transcription physiology” of pigment formation in melanocytes: central role of MITF

J Vachtenheim, J Borovanský - Experimental dermatology, 2010 - Wiley Online Library
Please cite this paper as:“Transcription physiology” of pigment formation in melanocytes:
central role of (MITF). Experimental Dermatology 2010; 19: 617–627. Abstract: Melanin …

SWI/SNF chromatin remodeling complex is critical for the expression of microphthalmia-associated transcription factor in melanoma cells

J Vachtenheim, L Ondrušová, J Borovanský - Biochemical and biophysical …, 2010 - Elsevier
The microphthalmia-associated transcription factor (MITF) is required for melanocyte
development, maintenance of the melanocyte-specific transcription, and survival of …