Background: There is evidence that amyotrophic lateral sclerosis (ALS), also known as
motor neuron disease (MND), is more common in men than in women and that gender …

Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disorder in adults.
This fatal condition, due to degeneration of upper and lower motor neurons in spinal and …

Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disorder. While most
cases of ALS are sporadic, 10–15% are familial, and of these 15–20% possess a mutation in …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no known
cure. Approximately 90% of ALS cases are sporadic, although multiple genetic risk factors …

Amyotrophic lateral sclerosis (ALS) is a severe progressive neurodegenerative disease. The
cause is unknown, but genetic abnormalities have been identified in subjects with familial …

Amyotrophic lateral sclerosis (ALS) is a heterogeneous group of neurological conditions
which have in common the progressive degeneration of upper and lower motor neurons …

Transgenic mice that overexpress the mutant human SOD1 gene (hSOD1) serve as an
animal model for amyotrophic lateral sclerosis (ALS). Age and sex are recognized as risk …

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder of
unknown etiology. ALS onset is rare before age 40 and increases with age thereafter. Men …

Objective The only identified cause of amyotrophic lateral sclerosis (ALS) are mutations in a
number of genes found in familial cases but also in sporadic cases. De novo mutations …

Importance This study reports the long-term epidemiologic trends of amyotrophic lateral
sclerosis (ALS) based on a prospective register. Objective To examine the 20-year …