Efficient co-transduction of adenoviral vectors encoding carcinoembryonic antigen and survivin into dendritic cells by the CAR-TAT adaptor molecule enhance anti …

HS Kim, CH Kim, MY Park, JS Park, HM Park, HJ Sohn… - Immunology letters, 2010 - Elsevier
Because multiple tumor antigens, including carcinoembryonic antigen (CEA) and survivin
(SVV), have been frequently observed in human colorectal cancer, we investigated whether …

In vitro induction of carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes by dendritic cells transduced with recombinant adenoviruses

HI Cho, HJ Kim, ST Oh, TG Kim - Vaccine, 2003 - Elsevier
Carcinoembryonic antigen (CEA), which is expressed in several cancer types, is a potential
target for specific immunotherapy. In this study, the feasibility of using dendrite cells (DCs) …

Protective anti-tumour immune responses by murine dendritic cells pulsed with recombinant Tat-carcinoembryonic antigen derived from Escherichia coli

MY Bae, NH Cho, SY Seong - Clinical & Experimental …, 2009 - academic.oup.com
Carcinoembryonic antigen (CEA) is over-expressed on various human cancer cells and has
been the target of immunotherapies using dendritic cells (DCs) pulsed with CEA-specific …

Inhibition and promotion of tumor growth with adeno-associated virus carcinoembryonic antigen vaccine and Toll-like receptor agonists

PL Triozzi, W Aldrich, S Ponnazhagan - Cancer gene therapy, 2011 - nature.com
Carcinoembryonic antigen (CEA) is a cancer vaccines' target. Several features of
recombinant adeno-associated virus (rAAV) are attractive for vaccine applications …

Modification of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC vaccination

SG Kim, MY Park, CH Kim, HJ Sohn, HS Kim, JS Park… - Vaccine, 2008 - Elsevier
Carcinoembryonic antigen (CEA) is expressed on human colon carcinomas, is well
characterized, and continues to be a promising target for cancer immunotherapy in humans …

Successful cancer vaccine therapy for carcinoembryonic antigen (CEA)‐expressing colon cancer using genetically modified dendritic cells that express CEA and T …

T Ojima, M Iwahashi, M Nakamura… - … journal of cancer, 2007 - Wiley Online Library
This study was designed to determine whether the vaccination of genetically modified
dendritic cells (DCs) simultaneously expressing carcinoembryonic antigen (CEA) …

Dendritic cells transduced with recombinant adenoviruses induce more efficient anti-tumor immunity than dendritic cells pulsed with peptide

ST Oh, CH Kim, MY Park, EH Won, HJ Sohn, HI Cho… - Vaccine, 2006 - Elsevier
Transduction with recombinant, replication-defective adenovirus (AdV) vectors encoding a
transgene is an efficient method for gene transfer into murine or human dendritic cells (DC) …

Dendritic cells transduced with tumor-associated antigen gene elicit potent therapeutic antitumor immunity: comparison with immunodominant peptide-pulsed DCs

M Nakamura, M Iwahashi, M Nakamori, K Ueda… - Oncology, 2005 - karger.com
Several studies have shown that vaccine therapy using dendritic cells (DCs) pulsed with
specific tumor antigen peptides can effectively induce antitumor immunity. Peptide-pulsed …

A loss of antitumor therapeutic activity of CEA DNA vaccines is associated with the lack of tumor cells' antigen presentation to Ag-specific CTLs in a colon cancer …

E Ahn, H Kim, KT Han, JI Sin - Cancer letters, 2015 - Elsevier
Human colon cancers express carcinoembryonic antigen (CEA). Thus, CEA has been
considered as a potential vaccine target for immune therapy against colon cancer. In this …

[PDF][PDF] Transgene expression in dendritic cells to induce antigen-specific cytotoxic T cells in healthy donors

R Philip, E Brunette, J Ashton, S Alters… - Cancer Gene …, 1998 - researchgate.net
Immunization with specific tumor-associated antigen (Ag)(TAA)-pulsed dendritic cells (DC)
has proven to be eficacious in a variety of animal models and is being investigated for the …