ABSTRACT A small probe (0= 2 mm) was designed to measure locally the optical properties
of biological tissues. The sensitivity of the measured Signal was assessed by experiments …

Purpose: To investigate the time courses of concentration changes using near–infrared
spectroscopy (NIRS) in oxyhemoglobin (oxy–Hb), deoxyhemoglobin (deoxy–Hb), and total …

Near-infrared spectroscopy and imaging are powerful tools to detect and continuously
monitor the cerebral hemodynamic and oxygenation changes induced by brain activity …

Incorporating the wavelength dependence of the scattering effect into a simple linear
multicomponent analysis of intrinsic optical signals, we have reexamined the change in the …

Brain activity is associated with changes in optical properties of brain tissue. Optical
measurements during brain activation can assess haemoglobin oxygenation, cytochrome-c …

We present near-infrared spectroscopy measurement of absolute cerebral hemoglobin
concentration and saturation in a large sample of 36 healthy elderly (mean age, 85±6 years) …

We present in vivo values for the optical transport coefficients (μ_a, μ_s′) of the adult
human forearm, calf, and head from 760 to 900 nm measured with time-resolved …

Near‐infrared spectroscopy (NIRS), a noninvasive optical technique, can measure changes
in hemoglobin (Hb) concentrations in brain tissue. Jöbsis first described the in vivo …

A general physiological model for the hemodynamic response during altered blood flow,
oxygenation, and metabolism is presented. Calculations of oxy-, deoxy-, and total …

When a pulse of light propagates through scattering media, the temporal information of the
light carries can be used to extract the optical properties of the media. To achieve this goal …