Objective To systematically review evidence on the efficacy and safety of sleep deprivation
(SD) as a treatment option for patients with unipolar or bipolar depression. Methods A …

Sleep deprivation, alone or in combination with pharmacological treatment and as part of a
chronotherapy package, is of potential use for people with major depressive episodes …

Backgrounds Depression is the most common mental disorder in the world. Sleep
deprivation (SD) is a well-known antidepressant. Several recombination protocols (including …

Total sleep deprivation (TSD) for one whole night improves depressive symptoms in 40–
60% of treatments. The degree of clinical change spans a continuum from complete …

Background: There are clinical as well as experimental indications that–contrary to what is
generally assumed—late partial sleep deprivation (LPSD) is not as effective as total sleep …

Growing clinical evidence in support of the efficacy and safety of sleep deprivation (SD), and
its biological mechanisms of action suggest that this technique can now be included among …

Background Bipolar disorder is a disabling disease characterized by the recurrence of mood
episodes. Successful strategies for the acute treatment of bipolar depression are still a …

Objective: To provide a quantitative meta-analysis of the antidepressant effects of sleep
deprivation to complement qualitative reviews addressing response rates. Data Sources …

Poor sleep is a significant risk factor for depression across the lifespan and sleep problems
have been hypothesised to contribute to the onset and maintenance of depression …

Sleep deprivation (SD) is a powerful antidepressant treatment that shows antidepressant
responses within hours in 40–60% of depressed patients. In more than 80% of responders …