The physiological approach is a serviceable method for interpreting acid-base disorders [1,
2]. The anion gap can be helpful in narrowing the differential diagnosis in a patient with …

The calculation of the 'anion gap'(AG) is common practice in the diagnostic workup of
patients with a metabolic acidosis. The AG is mostly calculated by subtracting the anions …

The anion gap is used to evaluate disturbances in the acid-base balance, in particular
metabolic acidosis. Due to the introduction of new clinical chemical techniques and modern …

The serum anion gap, calculated from the electrolytes measured in the chemical laboratory,
is defined as the sum of serum chloride and bicarbonate concentrations subtracted from the …

Not all metabolic acidosis is associated with an elevated chloride replacing the low
bicarbonate concentration. When other acids, usually non-Cl organic acids are introduced …

Both increased and reduced anion gap have clinical significance, but the deviation from
normal that has most clinical significance is increased anion gap associated with metabolic …

The serum anion gap (AG), a tool for acid–base assessment, is generally calculated from
sodium, chloride, and bicarbonate concentration ([Na+],[Cl–], and [HCO3–], respectively, in …

Abstract Evaluation of a presumed metabolic acidosis begins with the clinical history and
assessment of potential causes of decreased plasma bicarbonate levels. Calculation of the …

Acid–base homeostasis is fundamental for life. The body is exceptionally sensitive to
changes in pH, and as a result, potent mechanisms exist to regulate the body's acid–base …

Anion gap (AG) is a calculated value commonly used in clinical practice. It approximates the
difference between the concentration of unmeasured anions (UA) and unmeasured cations …