In Canada, the fifth dose of the routine childhood immunization schedule against diphtheria,
tetanus, pertussis and polio is given at 4–6 years of age. Up to 30% of children may have …

The annual contact for influenza vaccination provides an opportunity to ensure that adults
have received other recommended vaccines such as Tdap. Healthy 19–64 year-olds were …

Background: The objective of this study was to assess the immunogenicity and
reactogenicity of the combined adsorbed tetanus toxoid, low dose diphtheria toxoid, 5 …

Background. Pertussis is increasingly recognized as an important cause of cough illness in
adolescents and adults. Purpose. To evaluate the safety and antibody response to a single …

BACKGROUND: Although decennial adult boosters of tetanus and diphtheria toxoids are
recommended in Canada and the United States, a second dose of pertussis vaccine is not …

Background: Adult formulation tetanus and diphtheria toxoids and acellular pertussis
vaccines (Tdap) have been developed to prevent pertussis in adolescents and adults. There …

Pertussis is a highly contagious disease, for which periodic peaks in incidence and an
increasing number of outbreaks have been observed over the last decades. The reduced …

BACKGROUND. The incidence of pertussis is increasing, especially in adolescents,
attributed in part to waning of immunity after childhood immunization. Recently licensed in …

Objective. To compare the safety and immunogenicity of 12 different acellular pertussis
vaccines combined with diphtheria and tetanus toxoids (DTaP) with one licensed diphtheria …

A sixth dose of tetanus, diphtheria, acellular pertussis (Tdap) vaccine in adolescents might
produce a differing reactogenicity and/or immunogenicity response depending on the …