The intestinal epithelium sits at the interface between an organism and its luminal
environment, and as such is prone to oxidative damage induced by luminal oxidants …

The intestinal tract, known for its capability for self-renew, represents the first barrier of
defence between the organism and its luminal environment. The thiol/disulfide redox …

Mucosal proliferation, together with differentiation and apoptosis, are a continuous
homeostatic process in the intestinal epithelium. The glutathione/glutathione disulfide redox …

Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …

Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

Extracellular redox (reduction–oxidation) state is a factor that serves as an important
regulator of cell–microenvironmental interactions and is determined by several known …

Oxidative stress involves the increased production and accumulation of free radicals,
peroxides, and other metabolites that are collectively termed reactive oxygen species (ROS) …

Inflammatory bowel disease (IBD) is associated with the production of reactive species that
target cysteine redox switches in proteins, thereby affecting gene regulation, DNA damage …

Reactive oxygen and nitrogen species are currently considered not only harmful byproducts
of aerobic respiration but also critical mediators of redox signaling. The molecules and the …