METHODS Measurement of the acute blood pressure decrease and the attenuation or
potentiation of exogenous angiotensin I-induced or bradykinin—induced blood pressure …

1. Captopril infused into sodium-loaded dogs produced a fall in both blood pressure [117+/-
9.7 to 96.6+/-11.4 (SD) mmHg] and plasma angiotensin II [11.0+/-3.0 to 1.6+/-1.3 (SD) …

The effects of hydralazine (3 mg/kg) and the angiotensin 1-converting enzyme (ACE)
inhibitor captopril (SQ 14,225)(100 mg/kg) on mean arterial blood pressure, plasma renin …

Oral administration of the angiotensin converting enzyme inhibitor, captopril (30 mg/kg per
day) to spontaneously hypertensive rats of the Okamoto strain progressively reduced arterial …

This study was conducted to examine the role of bradykinin in the persistence of the renal
vasodilator effect of captopril during angiotensin II receptor blockade. Blood pressure and …

METHODS Male Splague-Dawley rats weighing 120-140 g were fed a standard rat chow
(Oriental Yeast Co., Tokyo), containing 0.44% sodium chloride, and tap water ad libitum. All …

Captopril (0.15-10 mg/kg) administration in the anesthetized dog causes immediate
hypotension concomitant with an increase in tonus of the assay tissue (cat terminal ileum) …

The effect of intravenous (iv) captopril on mean arterial blood pressure (MABP) of
anaesthetized normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) …

The acute hypotensive effect of captopril 25 mg was investigated in 26 hypertensive patients
(11 with essential and 15 with renal arterial disease). Intra-arterial blood pressure was …

Abstract Treatment of pentobarbital-anaesthetized rats with captopril (SQ 14225) caused a
reduction in mean arterial blood pressure (MAP), which lasted for over 1 h when a dose of 5 …