Chronic liver disease after low daily doses of amiodarone: report of three cases

G Babany, A Mallat, ES Zafrani, MFSM Girardin… - Journal of …, 1986 - Elsevier
A few cases of alcohol-like chronic liver disease have recently been described in patients on
high daily doses of amiodarone (400–600 mg) for 5–24 months. We report here 3 cases in …

Acute hepatitis induced by parenteral amiodarone

SA Gregory, JB Webster, GD Chapman - The American journal of …, 2002 - amjmed.com
Hepatic dysfunction, most commonly an elevation of aminotransferases, develops in 15% to
40% of patients receiving amiodarone (1). However, acute hepatitis induced by parenteral …

Probable early acute hepatitis with parenteral amiodarone

J Lupon‐Rosés, R SimÓa‐Canonge… - Clinical …, 1986 - Wiley Online Library
A patient with acute changes suggesting acute hepatitis after parenteral amiodarone
administration is described. A 77‐year‐old man with previous myocardial infarction was …

Rapidly fatal acute amiodarone hepatitis occurring in the context of multiple organ failure

RJ MacFadyen, TJ Palmer… - International …, 2003 - internationaljournalofcardiology.com
Amiodarone remains the agent of choice for the 80 mmHg and clinical and radiological
evidence of management of atrial fibrillation in unstable patients fluid overload. He was …

Acute amiodarone-induced hepatitis.

N Kalantzis, P Gabriel, J Mouzas, D Tiniakos… - Hepato …, 1991 - europepmc.org
Two fatal cases of amiodarone-induced acute, confluent, necrotic hepatitis are described.
The patients, aged 28 and 60, had received a high loading dose of amiodarone. After the …

Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha

J Lu, AD Jones, JR Harkema, RA Roth… - Toxicological …, 2012 - academic.oup.com
Abstract Amiodarone [2-butyl-3-(3′, 5′-diiodo-4'α-diethylaminoethoxybenzoyl)-
benzofuran](AMD), a class III antiarrhythmic drug, is known to cause idiosyncratic …

Multisystem side effects of amiodarone

SU Rehman, N Siddiqui, NS Khan, R Sobia… - The American journal …, 2015 - amjmedsci.com
A60-year-old man with medical history of atrial fibrillation on amiodarone 400 mg/d for 8
years was admitted for increased shortness of breath. On his general physical examination …

[HTML][HTML] Amiodarone-induced multi-systemic toxicity involving the liver, lungs, thyroid, and eyes: a case report

HS You, JH Yoon, SB Cho, YD Choi, YH Kim… - Frontiers in …, 2022 - frontiersin.org
Objectives Amiodarone is widely used to treat arrhythmia. However, amiodarone is known
for its severe toxicity to the liver, lungs, and thyroid. Amiodarone causes liver damage …

Establishment of a mouse model for amiodarone‐induced liver injury and analyses of its hepatotoxic mechanism

S Takai, S Oda, K Tsuneyama, T Fukami… - Journal of Applied …, 2016 - Wiley Online Library
Drug‐induced liver injury (DILI) is the most frequent cause of post‐marketing warnings and
withdrawals. Amiodarone (AMD), an antiarrhythmic, presents a risk of liver injury in humans …

Rapid acute amiodarone-induced hepatotoxicity in a burn patient

AV Maker, DP Orgill - Journal of Burn Care & Rehabilitation, 2005 - academic.oup.com
Acute burn and trauma patients have a higher frequency of cardiac arrhythmias than would
be expected for noncardiac-hospitalized patients. Amiodarone is an effective, commonly …