Objective: Therapeutic sleep deprivation (SD) is a nonpharmacological treatment that is
used most often for depression. The aim of this study was to examine the pattern of use of …

Objective To systematically review evidence on the efficacy and safety of sleep deprivation
(SD) as a treatment option for patients with unipolar or bipolar depression. Methods A …

Background Sleep deprivation (SD) is an antidepressant intervention with multiple
administration formats that has been investigated primarily with uncontrolled clinical trials …

Sleep deprivation therapy (SDT), also referred to as “wake therapy,” is a robust, rapid-acting
(within 24–48 hours), noninvasive antidepressant treatment. First proposed by Schulte1 and …

Background: There are clinical as well as experimental indications that–contrary to what is
generally assumed—late partial sleep deprivation (LPSD) is not as effective as total sleep …

Although there is a body of literature on the therapeutic efficacy of sleep deprivation (SD)
there are only a few investigations in which the relevance of antidepressive medication for …

Total sleep deprivation (TSD) for one whole night improves depressive symptoms in 40–
60% of treatments. The degree of clinical change spans a continuum from complete …

Sleep disorder is one of the major symptoms in depression. It can be a risk factor, predictor,
or symptom of depressive episodes. Successful therapy of sleep disorder in severely …

Sleep deprivation (SD) induces a rapid amelioration of mood in about 60% of depressed
patients. After the next night of sleep, however, most patients experience a relapse. Previous …

The literature suggests that sleep deprivation can potentiate the effect of antidepressant
medication in depressed patients. However, the clinical efficacy of sleep deprivation has not …