High solubility, high permeability and good stability are basic prerequisites for achieving the
bioavailability and hence therapeutic effectiveness. Newly developed drugs having poor …

Adequate aqueous solubility has been one of the desired properties while selecting drug
molecules and other bio-actives for product development. Often solubility of a drug …

A drug is effective in their molecular form; thus solubility in the biological fluid is important.
Pharmaceutical researchers are continuously working on the improvement of solubility of …

Sufficient fluid solvency has been one in everything about required properties while
choosing drug particles and completely uncommon bio-actives for advancement. Here and …

Poor solubility and hydrophobicity of drugs/bioactives limit their possible applications in drug
delivery and formulation development. Apart from conventional methods of solubility …

Objective: Dendrimers, a new class of synthetic polymers proved themselves very useful
tools for biomedical application due to their unique characteristics including water solubility …

Solubility of a drug influences the behavior of compounds in biomedical applications. Poor
solubility of drugs and hydrophobicity along with other bioactive compounds limit their …

Dendrimers today are known for their three dimensional, monodispersed, highly branched,
macromolecular nano-scopic architecture with number of reactive end groups. Dendrimers …

Dendrimers - reflections on host-guest interaction mechanism towards solubility enhancement
Page 1 188 Asian Journal of Pharmaceutics - July-September 2009 INTRODUCTION In the …

Hydrophobicity of drugs and bioactive compounds reduces their solubility in water and
significantly diminishes their activity in vivo [21]. Only 60% of drug candidates reach the …